Bijesh Kumar Biswal

Associate Professor & Warden (Homi Bhabha Hall of Residence)

Life Science

 (+91) 661 246 2785

 biswalb[at]nitrkl.ac.in

 Biosketch

32

Publications       

3

Sponsored Projects

0

Consultancy Projects

7

Doctoral Students

0

Continuing Education

12

PG Dissertation

 Personal Information

Prof. Bijesh Kumar Biswal

Associate Professor

Life Science

Joined in Jul 2015

 Room Number: MN-337

 Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

 Education Qualification

  1. Ph.D.(IIT Madras)

 Experience

No Experience Found....

 Expertise Information

Research Group
Biochemistry and Molecular Biology
Areas of Interest
Cancer and Stem Cell Biology - Cancer and Stem Cell Biology, Drug Resistance in Cancer

 Projects

Deciphering role of autophagy in stemness and therapy resistance in oral cancer stem cells

 DBT

 Co-Investigator

 36 months

 Completed

Sponsored

Excogitate neoteric biomakers for Lungs Cancer: a tissue oriented study of Lungs Cancers patients in Odisha

 Science & Technology Department,Govt Of Odisha

 Principal Investigator

 36 months

 Completed

Sponsored

Elucidate the epigenetic role of sox9 in tkls resistant non small cell lung cancer

 SERB

 Principal Investigator

 36 months

 Completed

Sponsored

 Continuing Education

No Continuing Educations Found....

 Publications

6

Google Scholar h-index

6

Google Scholar i10-index

Scopus h-index

Total Publications: 32
S. Biswal, M. Panda, R. K. Sahoo, S. K. Tripathi, and B. K. Biswal, "Tumour microenvironment and aberrant signaling pathways in cisplatin resistance and strategies to overcome in oral cancer", Archives of Oral Biology, vol.151, Elsevier, July 2023, https://doi.org/10.1016/j.archoralbio.2023.105697 Article
S. K. Padhan, J. Bag, M. Panda, B. K. Biswal, H. Sahoo, M. Mishra, and S. N. Sahu, "Synthesis of First Coumarin Fluorescent Dye for Actin Visualization.", Bioconjugate Chemistry, ACS, October 2022, 10.1021/acs.bioconjchem.2c00332 Article
M. Panda, S. K. Tripathi, G. Zengin, and B. K. Biswal, "Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers.", Cell Biology and Toxicology, Springer, September 2022, 10.1007/s10565-022-09772-8 Article
S. Mund, K. Singh, M. Panda, B. K. Biswal, U. Subuddhi, and V. S. Kumar, "Thiabendazole: a new class of antenna core structure for multifunctional trivalent organo-europium (EuIII) complexes", Journal of Materials Chemistry C, RSC, June 2022, DOI https://doi.org/10.1039/D2TC01078J Article
M. Panda and B. K. Biswal, "Evodiamine inhibits stemness and metastasis by altering the SOX9–ß-catenin axis in non-small-cell lung cancer", Journal of Cellular Biochemistry, Wiley 2022, https://doi.org/10.1002/jcb.30304 Article

Show All Publications(+)

S. Kanttripathi, R. K. Sahoo, and B. K. Biswal, "SOX9 as an emerging target for anticancer drugs and a prognostic biomarker for cancer drug resistance", Drug Discovery Today, Elsevier 2022, https://doi.org/10.1016/j.drudis.2022.05.022 Article
S. Chabattula, P. Gupta, S. Tripathi, R. Gahtori, P. Padhi, S. Mahapatra, B. K. Biswal, S. Singh, K. Dua, J. Ruokolainen, Y. Mishra, N. Jha, D. Bishi, and K. Kesari, "Anticancer therapeutic efficacy of biogenic Am-ZnO nanoparticles on 2D and 3D tumor models", Materials Today Chemistry, vol.22, no.100618, Elsevier, December 2021, https://doi.org/10.1016/j.mtchem.2021.100618 Article
N. Nayak, A. B. Shaik, S. K. Tripathi, B. K. Biswal, M. Mishra, and D. Sarkar, "Non-cytotoxic and non-genotoxic wear debris of strontium oxide doped (Zirconia Toughened Alumina) (SrO-ZTA) implant for hip prosthesis", Materials Chemistry and Physics, vol.274, no.125187, December 2021, https://doi.org/10.1016/j.matchemphys.2021.125187 Article
S. K. Tripathi and B. K. Biswal, "SOX9 promotes epidermal growth factor receptor-tyrosine kinase inhibitor resistance via targeting ß-catenin and epithelial to mesenchymal transition in lung cancer", Life Sciences, vol.277, Elsevier, July 2021 Article
S. K. Tripathi and B. K. Biswal, "Allosteric mutant-selective fourth-generation EGFR inhibitors as an efficient combination therapeutic in the treatment of non-small cell lung carcinoma", Drug Discovery Today, vol.26, Elsevier, June 2021, https://doi.org/10.1016/j.drudis.2021.02.005 Article
M. Panda, S. K. Tripathi, and B. K. Biswal, "SOX9: An emerging driving factor from cancer progression to drug resistance", Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1875, Elsevier, April 2021, https://doi.org/10.1016/j.bbcan.2021.188517 Article
S. K. Tripathi and B. K. Biswal, "Piperlongumine, a potent anticancer phytotherapeutic: Perspectives on contemporary status and future possibilities as an anticancer agent", Pharmacological Research, vol.156, no.104772, Elsevier, June 2020, 10.1016/j.phrs.2020.104772 Article
K. Pandey, S. K. Tripathi, M. Panda, and B. K. Biswal, "Prooxidative activity of plumbagin induces apoptosis in human pancreatic ductal adenocarcinoma cells via intrinsic apoptotic pathway", Toxicology In Vitro, vol.65, Elsevier, June 2020, 10.1016/j.tiv.2020.104788 Article
M. Panda, S. K. Tripathi, and B. K. Biswal, "Plumbagin promotes mitochondrial mediated apoptosis in gefitinib sensitive and resistant A549 lung cancer cell line through enhancing reactive oxygen species generation", Molecular Biology Reports, vol.47, pp.4155-4168, Springer, May 2020, 10.1007/s11033-020-05464-w Article
S. K. Tripathi, K. R. Rengasamy, and B. K. Biswal, "Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction", Archives of Pharmacal Research, vol.43, pp.242-256, Springer, February 2020, 10.1007/s12272-020-01221-6 Article
B. K. Biswal, "Plumbagin reduces proliferation and survival of non-small cell lung carcinoma irrespective of gefitinib resistance", in National Conference on Advances in Life Sciences and Biotechnology, Rma Devi Womens University Bhubaneswar, February 2020 Inproceedings
S. K. Tripathi, S. Behera, M. Panda, G. Zengin, and B. K. Biswal, "A Comprehensive Review on Pharmacology and Toxicology of Bioactive Compounds of Lagerstroemia Speciosa(L.) Pers.", Current Traditional Medicine 2020, 10.2174/2215083806999201211213931 Article
S. K. Tripathi, K. Pandey, K. R. Rengasamy, and B. K. Biswal, "Recent updates on the resistance mechanisms to epidermal growth factor receptor tyrosine kinase inhibitors and resistance reversion strategies in lung cancer", Medicinal Research Reviews, Wiley 2020, 10.1002/med.21700 Article
B. K. Biswal, S. K. Tripathi, M. Panda, and K. Pandey, "SOX9 promotes gefitinib resistance in non-small cell lung carcinoma through differential expression of epithelial to mesenchymal transition markers", in International Conference “Cancer Metastasis”, December 2019 Inproceedings
K. Pandey, S. K. Tripathi, and B. K. Biswal, "Cytotoxic and apoptotic potential of plumbagin in human pancreatic carcinoma cells through mitochondrial mediated pathway", in 4th International Conference on “Nutraceuticals and Chronic Diseases”, September 2019 Inproceedings
S. K. Tripathi, K. Pandey, M. Panda, M. Spinella, K. R. Rengasamy, and B. K. Biswal, "The potential of retinoids for combination therapy of lung cancer: updates and future directions", Pharmacological Research, vol.147, no.104331, Elsevier, September 2019, 10.1016/j.phrs.2019.104331 Article
S. K. Tripathi and B. K. Biswal, "C797S Mutation in Resistance Development to Third-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Lung Cancer", Austin Oncology, Austin Publishing Groups, August 2019 Article
S. K. Tripathi, M. Panda, and B. K. Biswal, "Emerging role of plumbagin: cytotoxic potential and pharmaceutical relevance towards cancer therapy", Food and Chemical Toxicology, vol.125, pp.566-582, Elsevier, March 2019, 10.1016/j.fct.2019.01.018 Article
S. K. Tripathi, A. K. Mahakud, and B. K. Biswal, "A green approach towards formulation, characterization, and antimicrobial activity of poly (Lactic-co-Glycolic) acid-Alstonia scholaris based nanoparticle", Mater. Res. Express, vol.6, IOP 2019, 10.1088/2053-1591/ab30d1 Article
M. Panda and B. K. Biswal, "Cell signaling and cancer: a mechanistic insight into drug resistance", Molecular Biology Reports, Springer 2019, 10.1007/s11033-019-04958-6 Article
S. K. Tripathi, K. Pandey, M. Panda, and B. K. Biswal, "Emerging roles of microRNAs as a regulator in the progression of lung cancer and their implications in its diagnosis and therapy", AGO-Driven Non-Coding RNAs : Codes to Decode the Therapeutics of Diseases, ch.11, pp.293-318, Elsevier 2019, 10.1016/B978-0-12-815669-8.00011-7 Inbook
P. K. Gupta, S. K. Tripathi, S. Pappuru, S. C. Chabattula, K. Govarthanan, S. Gupta, B. K. Biswal, D. Chakraborty, and R. S. Verma, "Metal-free semi-aromatic polyester as nanodrug carrier: A novel tumor targeting drug delivery vehicle for potential clinical application", Materials Science and Engineering C, vol.107, Elsevier 2019, 10.1016/j.msec.2019.110285 Article
B. K. Biswal and S. K. Tripathi, "Phytotherapeutic potential of Pterospermum acerifolium L. in human cancer cell lines through mitochondrial mediated ROS generation", in National Conference on Biodiversity, Biotechnology & Bioinformatics: Innovative and Emerging Trends-2019 2019 Inproceedings
S. K. Tripathi and B. K. Biswal, "Pterospermum acerifolium (L.) wild bark extract induces anticarcinogenic effect in human cancer cells through mitochondrial-mediated ROS generation", Molecular Biology Reports, vol.45, no.6, pp.2283-2294, Springer, December 2018, 10.1007/s11033-018-4390-6 Article
S. K. Tripathi and B. K. Biswal, "Mechanistic investigation of anticancer potential of Pterospermum acerifolium bark extract in human cancer cell lines through ROS generation and mitochondrial stress pathway", in 37th Annual convention of Indian association of cancer research and symposium. 2018 Inproceedings
S. K. Tripathi and B. K. Biswal, "Plumbagin inhibits growth and induced apoptosis through mitochondrial stress and reactive oxygen species generation in lung cancer cells", in 87 Annual Conference of Society of Biological Chemists India 2018 Inproceedings
B. K. Biswal and S. K. Tripathi, "Wnt/b-catenin: the main culprit behind Cancer Chemoresistance", Journal of Applied Microbiology and Biochemistry, vol.1, no.4, pp.16, iMedPub, September 2017, 10.21767/2576-1412.100016 Article

 Courses Taught

  • LS100 : Biology {Theory}
  • LS1001 : Biology {Theory}
  • LS206 : Cell and Molecular Biology {Theory}
  • LS2101 : Basic Biochemistry {Theory}
  • LS2401 : Cell and Molecular Biology {Theory}
  • LS305 : Physiology {Theory}
  • LS3102 : Physiology {Theory}
  • LS320 : Stem Cell Biology {Theory}
  • LS6013 : Research Methodology {Theory}
  • LS613 : Research Methodology {Theory}
  • LS2091 : Life Science Laboratory- I {Practical}
  • LS2092 : Life Science Laboratory- II {Practical}
  • LS276 : Cell and Molecular Biology laboratory {Practical}
  • LS375 : Physiology Laboratory {Practical}

 Research Scholars

Ph.D. Students [7]
Investigation of SOX9 Mediated Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance Reverting Potential of Piperlongumine in Lung Cancer

 Surya Kant Tripathi

Enrolled: Jan 2016

 Graduated : Dec 2021

 Supervisor

Iron Mineralization in Mycobacterial Ferritins: Impact of Protein Cage, Pores, and Phosphate

 Akankshika Parida

Enrolled: Sep 2017

 Graduated : Nov 2022

 Co-Supervisor

Evodiamine Resensitizes Cisplatin Resistance by Targeting SOX9-ß-catenin Axis in Non-small Cell Lung Cancer

 Munmun Panda

Enrolled: Jul 2017

 Graduated : Apr 2023

 Supervisor

Cancer biology

 Stuti Biswal

Enrolled: Jan 2020

 Continuing

 Supervisor

Biochemistry and Molecular Biology

 Rajeev Kumar Sahoo

Enrolled: Sep 2020

 Continuing

 Supervisor

Cell & Molecular Biology, Cancer Biology

 Sambit Kumar Patra

Enrolled: Jul 2022

 Continuing

 Supervisor

Cancer Biology

 Shikshya Swarupa Panda

Enrolled: Jan 2023

 Continuing

 Supervisor

 Dissertations

PG Dissertation
  • Amaresh Kumar Mahakud (415LS2058), "Preparation, characterization and antimicrobial activity of Alstonia scholaris leaf extract loaded PLGA nanoparticle" - M.Sc.    Supervisor     2016-17 Spring
  • Rakshin Malik (416LS2067), "Nanoparticle based herbal therapy from Pterospermum acerifolium and Terminalia arjuna for antibacterial and anticancer treatment" - M.Sc.    Supervisor     2017-18 Spring
  • Sunayna Behera (416LS2055), "Green synthesis of silver nanoparticles using Lagerstroemia speciosa and Tinospora cordifolia extracts and studying their anti-bacterial as well as anticancer effect" - M.Sc.    Supervisor     2017-18 Spring
  • Lipika Sha (417LS2072), "Biosynthesis, charecterization, and therapeutic effect of silver nanoparticle synthesized from Annona squamosa (L.)" - M.Sc.    Supervisor     2018-19 Spring
  • Sarita Barik (418LS2056), "SYNTHESIS, ENCAPSULATION AND CHARACTERIZATION OF SILVERNANOPARTICLE" - M.Sc.    Supervisor     2019-20 Spring
  • Yash Prinka (418LS2055), "Synthesis and characterization of silver nanoparticles by chemical and phytochemical methods and encapsulation of cisplatin in AgNP" - M.Sc.    Supervisor     2019-20 Spring
  • Titas Bain (419LS2062), "Statistical analysis of lung cancer and EGFR gene expression" - M.Sc.    Supervisor     2020-21 Spring
  • Akanksha Bhardwaj (420LS2179), "Targeting AKT/mTOR signaling pathway by inhibiting SOX2 via curcumin and cisplatin as a potential therapeutic in oral carcinoma." - M.Sc.    Supervisor     2021-22 Spring
  • Madhushmita Dhurua (420LS2177), "Investigating the role of SOX4 by targeting Ras Signalling pathway in colorectal cancer" - M.Sc.    Supervisor     2021-22 Spring
  • Sayed Mohamad Safwan (420LS2046), "Investigating the role of SOX9 in non-small cell lung cancer and targeting SOX9 by plumbagin to inhibit cancer progression and chemoresistance" - M.Sc.    Supervisor     2021-22 Spring
  • Neelam Gautam (421LS2068), "Targeting SOX2 using plumbagin and cisplatin as a potential therapeutic in non-small cell lung cancer" - M.Sc.    Supervisor     2022-23 Spring
  • Simran Gupta (421LS2169), "Targeting SOX4 using Piperlongumine and Oxaliplatin as Potential Therapeutics in Colorectal Cancer" - M.Sc.    Supervisor     2022-23 Spring
UG Dissertation
  • Biswaranjan Sahoo (415LS5063), "Analysis of phytochemical profile of bark and leaf extract of Terminalia arjuna" - Integrated M.Sc.    Supervisor     2019-20 Spring
  • Bikash Kisan (416LS5016), "Statistical data for Oral Cancer and Analysis of CA9 expression in oral cancer." - Integrated M.Sc.    Supervisor     2020-21 Spring

 Awards and Honours

Awards and Honours
  • ,   
Memberships / Fellowships
  • ,