Usharani Subuddhi

Associate Professor

Chemistry

 (+91) 661 246 2662 , 3662

 subuddhiu[at]nitrkl.ac.in

 Biosketch

33

Publications       

2

Sponsored Projects

0

Consultancy Projects

10

Doctoral Students

2

Continuing Education

12

PG Dissertation

 Personal Information

Prof. Usharani Subuddhi

Associate Professor

Chemistry

Joined in Jul 2009

 Room Number: MN-424

 Department of Chemistry, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

 Education Qualification

  1. Ph. D. (IIT Madras)

 Experience

Laboratory Development
  • Physical Photochemistry and Biophysical Laboratory,  NIT Rourkela,  The laboratory is equipped for carrying out research in the said field.

 Expertise Information

Research Group
Physical Chemistry
Areas of Interest
Physical Photochemistry and Fluorescence Spectroscopy, Biophysical Chemistry, Colloids and Surface Chemistry, Novel Drug Delivery Systems - My research interest mostly spans the following two areas: (i) Spectroscopic investigations of biological and biomimetic systems (Surfactants, Dendrimers, Cyclodextrins, Proteins, Liposomes etc.) (ii)Design and study of novel drug delivery systems.

 Projects

Design & Synthesis Of Multifunctional Micellar Based Drug Delivery Vehicles For Cancer Therapy

 BRNS

 Co-Investigator

 36 months

 Completed

Sponsored

Design and physico-chemical properties of cyclodextrin incorporated smart hydrogels: Towards improved delivery of hydrophobic drugs.

 DST

 Principal Investigator

 36 months

 Completed

Sponsored

 Continuing Education

“International Webinar on Frontiers in Organic Electronics”

 Chemistry

 Coordinator

 01 Apr 2022 - 02 Apr 2022

Conference

WEBINAR ON FRONTIERS IN CHEMICAL SCIENCES

 Chemistry

 Coordinator

 06 Jul 2020 - 10 Jul 2020

Conference

 Publications

11

Google Scholar h-index

12

Google Scholar i10-index

10

Scopus h-index

Total Publications: 33
M. Tripathy, S. Rana, U. Subuddhi, and S. Patel, "Simultaneous visual and spectroscopic multi-analyte detection of Al3+ and AsO2- using simple salicylidene based D-p-A chromophore", Journal of Photochemistry and Photobiology A: Chemistry, vol.435, no.114329, pp.1-17, Elsevier, February 2023, https://doi.org/10.1016/j.jphotochem.2022.114329 Article
S. Mund, K. Singh, M. Panda, B. K. Biswal, U. Subuddhi, and V. S. Kumar, "Thiabendazole: a new class of antenna core structure for multifunctional trivalent organo-europium (EuIII) complexes", Journal of Materials Chemistry C, RSC, June 2022, DOI https://doi.org/10.1039/D2TC01078J Article
S. Mohanty, B. Tirkey, S. R. Jena, L. Samanta, and U. Subuddhi, "Exploring steroidal surfactants as potential drug carriers for an anticancer drug curcumin: an insight into the effect of surfactants’ structure on the photophysical properties, stability, and activity of curcumin", Langmuir, vol.39, no.5, pp.1852-1869, American Chemical Society 2022, 10.1021/acs.langmuir.2c02797 Article
S. Mohanty and U. Subuddhi, "Fluorescence Lifetime: A Multifaceted Tool for Exploring Biological Systems", Optical Spectroscopic and Microscopic Techniques, ch.5, pp.77-112, Springer 2022, 10.1007/978-981-16-4550-1_5 Inbook
S. Das and U. Subuddhi, "Potential of guar gum hydrogels in drug delivery", Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine, ch.5, pp.143-172, Elsevier, woodhead publishing in biomaterials, June 2021, 10.1016/B978-0-12-821649-1.00006-4 Inbook

Show All Publications(+)

S. Mohanty and U. Subuddhi, "Unravelling the aggregation behaviour and micellar properties of CHAPS (3-[(3-cholamidopropyl)-dimethylamino]-1-propanesulfonate), a zwitterionic derivative of cholic acid, using Coumarin 1 photophysics", Journal of Photochemistry & Photobiology, A: Chemistry, Elsevier 2021, https://doi.org/10.1016/j.jphotochem.2021.113339 Article
S. Das, S. Mohanty, J. Maharana, S. Jena, J. Nayak, and U. Subuddhi, "Microwave-assisted ß-cyclodextrin/chrysin inclusion complexation: An economical and green strategy for enhanced hemocompatibility and chemosensitivity in vitro", Journal of Molecular Liquids, vol.310, no.113257, pp.1-11, Elsevier, April 2020, 10.1016/j.molliq.2020.113257 Article
S. Das and U. Subuddhi, "Alginate-based interpenetrating network carriers for biomedical applications", Interpenetrating Polymer Network: Biomedical Applications, ch.4, pp.79, Springer Nature, Department of Chemistry, NIT Rourkela, Rourkela, Odisha, India e-mail: subuddhiu@nitrkl.ac.in 2020, 10.1007/978-981-15-0283-5_4 Inbook
M. Tripathy, U. Subuddhi, and S. Patel, "An azo dye based D-p-A chromogenic probe for selective naked-eye detection of Hg2+ ion: application in logic gate operation", ChemistrySelect, vol.5, no.16, pp.4803 –4815, John Wiley & Sons 2020, 10.1002/slct.202000659 Article
M. Tripathy, U. Subuddhi, and S. Patel, "A styrylpyridinium dye as chromogenic and fluorogenic dual mode chemosensor for selective detection of mercuric ion: Application in bacterial cell imaging and molecular logic gate", Dyes and Pigments, vol.174, Elsevier, November 2019, 10.1016/j.dyepig.2019.108054 Article
S. S. Mishra, S. Mohanty, J. Mishra, and U. Subuddhi, "Photophysical properties of coumarin 1 in bile salt aggregates: an insight into the role of bile salt structure on the aggregation behavior", Langmuir, vol.35, no.50, pp.16555–16567, American Chemical Society 2019, 10.1021/acs.langmuir.9b02664 Article
S. Das, J. Maharana, S. Mohanty, and U. Subuddhi, "Spectroscopic and computational insights into theophylline/ß-cyclodextrin complexation: inclusion accomplished by diverse methods", Journal of Microencapsulation:Micro and Nano Carriers, Taylor & Francis 2019, 10.1080/02652048.2019.1572239 Article
. Subhraseemadas and U. Subuddhi, "Controlled Delivery of Ibuprofen from Poly(vinyl alcohol)-Poly(ethylene glycol) Interpenetrating Polymeric Network Hydrogels", Journal of Pharmaceutical Analysis, Elsevier 2018, 10.1016/j.jpha.2018.11.007 Article
S. Das and U. Subuddhi, "Guar gum–poly(N-isopropylacrylamide) smart hydrogels for sustained delivery of 5-fluorouracil", Polymer Bulletin, Springer 2018, 10.1007/s00289-018-2526-4 Article
S. Das and U. Subuddhi, "Controlled and targeted delivery of diclofenac sodium to the intestine from pH-Responsive chitosan/poly(vinyl alcohol) interpenetrating polymeric network hydrogels", Polymer Science Series A, vol.58, no.2, pp.154-166, Springer, March 2016, 10.1134/S0965545X16020048 Article
S. Das and U. Subuddhi, "Studies on the complexation of diclofenac sodium with ß-cyclodextrin: Influence of method of preparation", Journal of Molecular Structure, vol.1099, pp.482-489, Elsevier, November 2015, 10.1016/j.molstruc.2015.07.001 Article
S. Das and U. Subuddhi, "PH-Responsive guar gum hydrogels for controlled delivery of dexamethasone to the intestine", International Journal of Biological Macromolecules, vol.79, pp.856-863, Elsevier, August 2015, 10.1016/j.ijbiomac.2015.06.008 Article
S. S. Mishra and U. Subuddhi, "Spectroscopic investigation of interaction of Nile Blue A, a potent photosensitizer, with bile salts in aqueous medium", Journal of Photochemistry and Photobiology B: Biology, vol.141, pp.67-75, Elsevier, October 2014, 10.1016/j.jphotobiol.2014.09.013 Article
U. Subuddhi, P. V, C. A, and M. A. K, "Disaggregation induced solvatochromic switch: A study of dansylated polyglycerol dendrons in binary solvent mixture", Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, vol.128, pp.351-356, Elsevier, July 2014, 10.1016/j.saa.2014.02.150 Article
S. Das and U. Subuddhi, "Exploring poly(vinyl alcohol) hydrogels containing drug-cyclodextrin complexes as controlled drug delivery systems", Journal of Applied Polymer Science, vol.131, no.11, Wiley, June 2014, 10.1002/app.40318 Article
S. Das and U. Subuddhi, "Controlled delivery of dexamethasone to the intestine from poly(vinyl alcohol)-poly(acrylic acid) microspheres containing drug-cyclodextrin complexes: Influence of method of preparation of inclusion complex", RSC Advances, vol.4, no.46, pp.24222-24231, Royal Society of Chemistry, May 2014, 10.1039/c4ra02736a Article
S. Das and U. Subuddhi, "Cyclodextrin mediated controlled release of naproxen from pH-sensitive chitosan/poly(vinyl alcohol) hydrogels for colon targeted delivery", Industrial and Engineering Chemistry Research, vol.52, no.39, pp.14192-14200, ACS, September 2013, 10.1021/ie402121f Article
L. Reha, C. Hariharan, U. Subuddhi, S. Xia, C. Zhao, J. Beckman, T. Christian, and W. Konigsberg, "Structure of the 2-aminopurine-cytosine base pair formed in the polymerase active site of the RB69 Y567A-DNA polymerase", Biochemistry, vol.50, no.46, pp.10136-10149, ACS, October 2011, 10.1021/bi2014618 Article
U. Subuddhi, P. Vuram, A. Mishra, and A. Chadha, "Photophysical investigation of microenvironment in glycerol based dansylated polyether dendrons", Journal of Photochemistry and Photobiology: A Chemistry, vol.217, no.2-3, pp.411-416, Elsevier, January 2011, 10.1016/j.jphotochem.2010.11.015 Article
V. P. K, U. Subuddhi, K. S. T, C. A, and M. A. K, "Synthesis and aggregation properties of dansylated glycerol-based amphiphilic polyether dendrons", European Journal of Organic Chemistry, vol.2010, no.26, pp.5030-5040, John Wiley, September 2010, 10.1002/ejoc.201000575 Article
M. Mohapatra, U. Subuddhi, and A., "Photophysical behaviour of ground state anion and phototautomer of 3-hydroxyflavone in liposome membrane", Photochemical & Photobiological Sciences, vol.8, no.10, pp.1373–1378, Royal Society of Chemistry 2009, 10.1039/b905906g Article
U. Subuddhi, S. Haldar, S. Sankararaman, and A., "Unusual fluorescence spectral response of 1-(4-N,N-dimethylaminophenylethynyl)pyrene towards the thermotropic phase change in lipid bilayer membranes", Journal of Photochemistry and Photobiology A: Chemistry, vol.200, no.2-3, pp.381–387, Elsevier 2008, 10.1016/j.jphotochem.2008.09.001 Article
U. Subuddhi, M. Hogg, and L. Reha, "Use of 2-aminopurine fluorescence to study the role of the hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases", Biochemistry, vol.47, no.23, pp.6130–6137, ACS 2008, 10.1021/bi800211f Article
U. Subuddhi and A. Mishra, "Effect of sodium deoxycholate and sodium cholate on DPPC vesicles: a fluorescence anisotropy study with diphenylhexatriene", Journal of Chemical Sciences, vol.119, no.2, pp.169–174, Indian Academy of Sciences 2007 Article
U. Subuddhi and A. Mishra, "Micellization of bile salts in aqueous medium: a fluorescence study", Colloids and Surfaces B: Biointerfaces, vol.57, no.1, pp.102–107, Elsevier 2007, 10.1016/j.colsurfb.2007.01.009 Article
S. Mohanty, U. Subuddhi, S. Baskaran, and A. K. Mishra, "Photophysical properties of newkome-type dendrimers in aqueous medium", Photochemical & Photobiological Sciences, vol.6, no.11, pp.1164–1169, Royal Society of Chemistry 2007, 10.1039/b702968c Article
U. Subuddhi, S. Haldar, S. Sankararaman, and A. K. Mishra, "Photophysical behaviour of 1-(4-N,N-dimethylaminophenylethynyl)pyrene (DMAPEPy) in homogeneous media", Photochemical & Photobiological Sciences, vol.5, no.5, pp.459–466, Royal Society of Chemistry 2006, 10.1039/b600009f Article
U. Subuddhi and A. K. Mishra, "Prototropism of 1-hydroxypyrene in liposome suspensions: implications towards fluorescence probing of lipid bilayers in alkaline medium", Photochemical & Photobiological Sciences, vol.5, no.3, pp.283-290, Royal Society of Chemistry 2006, 10.1039/b513200b Article

 Courses Taught

  • CY101 : Chemistry {Theory}
  • CY1101 : Chemistry {Theory}
  • CY231 : Basic Physical Chemistry I {Theory}
  • CY3302 : Chemical Kinetics and Photochemistry {Theory}
  • CY4302 : Molecular Spectroscopy {Theory}
  • CY433 : Chemical Kinetics and Photochemistry {Theory}
  • CY532 : Chemical Kinetics and Photochemistry {Theory}
  • CY532 : Molecular Spectroscopy {Theory}
  • CY6306 : Special Topics in Physical Chemistry {Theory}
  • CY636 : Special Topics in physical chemistry {Theory}
  • CY7306 : Special Topics in Physical Chemistry {Theory}
  • CY2702 : Basic Physical Chemistry Laboratory - I {Practical}
  • CY272 : Basic Physical Chemistry Laboratory {Practical}
  • CY273 : Physical Chemistry Laboratory {Practical}
  • CY4703 : Physical Chemistry Laboratory {Practical}
  • CY475 : Physical Chemistry Laboratory – I {Practical}
  • CY573 : Physical Chemistry Laboratory {Practical}
  • CY573 : Physical Chemistry Laboratory – II {Practical}

 Research Scholars

Ph.D. Students [10]
Design and Physico-Chemical Properties of Cyclodextrin Incorporated Hydrogels: Application towards Controlled Delivery of Drugs

 Subhraseema Das

Enrolled: Jul 2010

 Graduated : Jan 2016

 Supervisor

Deciphering the Interaction of Steroidal Biosurfactants with Some Small Molecules and Macromolecules of Biological Relevance: A Photophysical Approach

 Smruti Snigdha Mishra

Enrolled: Jul 2011

 Graduated : Dec 2019

 Supervisor

Donor-pi-Acceptor Based Push-Pull Organic Chromophores: Chemosensing Application through Modulation in Intramolecular Charge Transfer

 Madhusmita Tripathy

Enrolled: Jul 2014

 Graduated : Aug 2021

 Co-Supervisor

Deciphering the Aggregation Behaviour of CHAPS, a Steroidal Zwitterionic Surfactant, and its Interaction with Biologically Important Molecules and Macromolecules: A Spectroscopic Approach

 Subhrajit Mohanty

Enrolled: Jul 2016

 Graduated : Dec 2022

 Supervisor

Molecular Engineering of Efficient Light Harvesting Organic Antennas for Multitasking Organo EuIII Complexes: Design, Synthesis, and Photophysical Investigations

 Sibani Mund

Enrolled: Jul 2018

 Graduated : Apr 2023

 Co-Supervisor

Design and synthesis of multifunctional micellar based drug delivery vehicles for cancer therapy.

 Aiswarya Pradhan

Enrolled: Jan 2019

 Continuing

 Co-Supervisor

Physical Photochemistry and Biophysical Chemistry

 Kuldeep

Enrolled: Jul 2019

 Continuing

 Supervisor

Physical Photochemistry and Biophysical Chemistry

 Binita Tirkey

Enrolled: Jul 2019

 Continuing

 Supervisor

Biophysical chemistry and photochemistry

 Chinmaya Pradhan

Enrolled: Jul 2022

 Continuing

 Supervisor

Biophysical Chemistry

 Salonee Swain

Enrolled: Jan 2023

 Continuing

 Supervisor

Executive Ph.D. Students [1]
Physical Photochemistry and Biophysical chemistry

 Kishan Kumar Agrawal

 Continuing

 Supervisor

 Dissertations

PG Dissertation
  • Anam Behera (413CY2004), "Inclusion Complex of Theophylline with ß-Cyclodextrin: Influence of Method of Preparation" - M.Sc.    Supervisor     2014-15 Spring
  • Ankit Kumar Gaur (414CY2008), "Effect of Bile Salts Microenvironment on the Photophysical Properties of Thionine" - M.Sc.    Supervisor     2015-16 Spring
  • Neha Barnwal (415CY2029), "Effect of Bile Salts Microenvironment on the Photophysical Properties of Methylene Blue" - M.Sc.    Supervisor     2016-17 Spring
  • Kuldeep (416CY2128), "Spectroscopic Investigation on Interaction of CHAPS with Human and Bovine Serum Albumin" - M.Sc.    Supervisor     2017-18 Spring
  • Mohan Tanti (416CY2051), "Preparation and Characterisation of Inclusion Complex of a-Naphthoflavone with ß-Cyclodextrin" - M.Sc.    Supervisor     2017-18 Spring
  • Prashant Sharma (417CY2052), "Evaluating Coumarin 466 as a Fluorescent Molecular Reporter for the Study of Micellisation of Bile Salts" - M.Sc.    Supervisor     2018-19 Spring
  • Anamika Gogoi (418CY2037), "Interaction of 4-[4-(Dimethylamino)styryl]-1-methylpyridinium dye with conventional and steroidal surfactants: A photophysical approach" - M.Sc.    Supervisor     2019-20 Spring
  • Amruta Dehury (419CY2044), "Chemical and Thermal denaturation of Bovine Serum Albumin in presence of CHAPS" - M.Sc.    Supervisor     2020-21 Spring
  • Soumyajit Gupta (419CY2045), "A Study on the Interaction of Piperine with Pepsin by Spectroscopic Methods." - M.Sc.    Supervisor     2020-21 Spring
  • Khan Suraiyya Khatoon Hafizurrehman Azizunnisa (420CY2028), "Photophysical Properties, Solubility and Stability of Curcumin in Surfactant Media: The Role of the Surfactant Head Group" - M.Sc.    Supervisor     2021-22 Spring
  • Aditya Narayan Sahoo (421CY2058), "Synthesis and Photophysical Properties of Dansyl labeled Lithocholic acid" - M.Sc.    Supervisor     2022-23 Spring
  • Kshiti Chandra Budek (421CY2041), "Synthesis and Photophysical Properties of Coumarin Conjugated Bile Acid Derivatives" - M.Sc.    Supervisor     2022-23 Spring
UG Dissertation
  • Rajkishore Mallik (410CY5014), "Controlled Release of Drug to the Intestine from pH-Responsive Chitosan ? Poly (vinyl alcohol) Interpenetrating Network Hydrogels" - Integrated M.Sc.    Supervisor     2014-15 Spring
  • Swaraj Rashmi Pradhan (411CY5097), "Environmental photocatalytic application of CuS modified Bi2WO6 nanomaterial" - Integrated M.Sc.    Co-supervisor     2015-16 Spring
  • Swagat Mohapatra (412CY5083), "Evaluation of four 7-Aminocoumarin Derivatives as Fluorescent Molecular Probes for Sensing the Microenvironmental Changes of Bile salts in Aqueous Medium" - Integrated M.Sc.    Supervisor     2016-17 Spring
  • Ved Prakash (413CY5007), "Effect of Steroidal Surfactants on the Physicochemical Properties of Curcumin: A Spectroscopic Study" - Integrated M.Sc.    Supervisor     2017-18 Spring
  • Sachidananda Nayak (414CY5049), "Interaction of Chrysin /ß Cyclodextrin Inclusion Complex with Bovine Serum Albumin: A Spectroscopic Study" - Integrated M.Sc.    Supervisor     2018-19 Spring
  • Soumyashree Jena (414CY5047), "Interaction between Zwitterionic Surfactant ‘CHAPS’ and Bovine Serum Albumin: A Spectroscopic Investigation" - Integrated M.Sc.    Supervisor     2018-19 Spring
  • Sachidananda Nayak (414CY5049), "Interaction of Chrysin /ß Cyclodextrin Inclusion Complex with Bovine Serum Albumin: A Spectroscopic Study" - Integrated M.Sc.    Supervisor     2019 Summer
  • Pragyansree Machhua (415CY5006), "Interaction between Hen Egg-White Lysozyme and Bile salts: A Spectroscopic study" - Integrated M.Sc.    Supervisor     2019-20 Spring
  • Harsh Kumar (417CY5067), "Synthesis and Photophysical Properties of Bile Acids Conjugated Anthracene" - Integrated M.Sc.    Supervisor     2021-22 Spring
  • Roshni Mahananda (418CY5003), "Preparation and Physico-Chemical Properties of Bile Acids Incorporated Tween Based Niosomes" - Integrated M.Sc.    Supervisor     2022-23 Spring

 Awards and Honours

No Awards/Honours Found....