sujitb

Academic Identity

Orcid Id

Scopus Id

14010303900

Researcher Id

Google Scholar Id

Sujit Kumar Bhutia

Associate Professor

Life Science

(+91) 661 246 2686 , 3686

sujitb[at]nitrkl.ac.in

Biosketch

144

Publications

15

0

Consultancy Projects

17

Doctoral Students

3

Continuing Education

20

PG Dissertation

Personal Information

Prof. Sujit Kumar Bhutia

Associate Professor

Life Science

Joined in Aug 2008

Room Number: MN-339

Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

Education Qualification

2009 Ph.D.
Cancer and cell death
Indian Institute of Technology Kharagpur

Experience

Teaching Experience

Cell Biology, National Institute of Technology Rourkela, 06 Aug 2008 - Present

Post Doctoral Research Experience

Autophagy and Cancer, Virginia Commonwealth University, 14 Oct 2008 - 12 Oct 2010

Expertise Information

Research Group

Cell and Developmental Biology

Areas of Interest

Cancer and cell death

Projects

Analysis of role of MTP18-dependent mitophagy in oral carcinogenesis and its targeting to activate m.

BRNS

Principal Investigator

36 months

Running

Sponsored

Deciphering MTP18 as an inner membrane mitophagy receptor in clearance of damaged mitochondria subdomains and its relevance in mitoptosis.

Science & Engineering Research Board(SERB)

Principal Investigator

36 months

Running

Sponsored

Analysis of Pax9 methylation in oral carcinogenesis and its reactivation leading to lethal autophagy for potential cancer therapeutics.

ICMR

Principal Investigator

36 months

Running

Sponsored

Stress induced clearance of dysfunctional Mitochondria through Puma dependent Mitophagy.

CSIR

Principal Investigator

60 months

Running

Sponsored

Genomewide profiling of PIWI0interacting RNAs (piRNAs) by Next-Generation Sequencing and investigating their role in Oral Squamous Cell Carcinoma.

DBT, Govt Of India

Co-Investigator

36 months

Completed

Sponsored

Deciphering role of autophagy in stemness and therapy resistance in oral cancer stem cells

DBT

Principal Investigator

36 months

Completed

Sponsored

Inspire and fist division dept of science & technology

DST-FIST

Principal Investigator

60 months

Completed

Sponsored

Stonin-2 regulated Beclin-1 dependent autophagy and autophagic lysosome reformation

Science & Engineering Research Board(SERB)

Principal Investigator

36 months

Completed

Sponsored

Protective autophagy by secretory clusterin associated with cell survival and chemoresistance in oral cancer

BRNS

Principal Investigator

36 months

Completed

Sponsored

Molecular Profiling of apoptotic pathway in cancer stem cells of oral squamous cell carcinoma and its modulating by plant lectins

DST,ODISHA

Principal Investigator

36 months

Completed

Sponsored

Autophagy induced by cellular Stress Switches to apoptosis

DBT

Principal Investigator

36 months

Completed

Sponsored

DNA DAMAGE-INDUCED P73-MEDIATED APOPTOSIS WITH ABRUS AGGLUTININ IN ORAL CANCER

CSIR

Principal Investigator

36 months

Completed

Sponsored

Deciphering role of cancer stem cells to therapy resistance in oral cancer

SERB

Principal Investigator

36 months

Completed

Sponsored

Autophagic cell death induction with Abrus agglutinin

DBT

Principal Investigator

36 months

Completed

Sponsored

Development of functionalized ferrite nanoparticles for targeted Tumor Therapy.

DBT

Co-Investigator

36 months

Completed

Sponsored

Continuing Education

2nd International Conference on Frontiers in Biological Sciences (InCoFIBS-2015)

Life Science

Coordinator

22 Jan 2015 - 24 Jan 2015

Brochure

Conference

Techniques to Understand Autophagic Processes in Mammalian Systems (TUAPMS)

Life Science

Coordinator

26 Feb 2020 - 01 Mar 2020

Brochure

Workshop

Workshop on Technologies on molecular Analysis of cell and cellular Dynamics (TMCCD)

Life Science

Coordinator

19 Nov 2015 - 21 Nov 2015

Brochure

Workshop

Publications

Google Scholar h-index

Google Scholar i10-index

0

Scopus h-index

Total Publications: 144

D. P. Panigrahi, S. Patra, B. P. Behera, P. K. Behera, S. Patil, B. S. Patro, L. Rout, I. Sarangi, and S. K. Bhutia, "MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer", Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA, vol.190, pp.307-319, Elsevier, September 2022, 10.1016/j.freeradbiomed.2022.08.019 Article

C. S. Bhol, S. R. Mishra, S. Patil, S. K. Sahu, R. Kirtana, S. Manna, M. K. Shanmugam, G. Sethi, S. K. Patra, and S. K. Bhutia, "PAX9 reactivation by inhibiting DNA methyltransferase triggers antitumor effect in oral squamous cell carcinoma", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1868, no.9, pp.166428, Elsevier, September 2022, 10.1016/j.bbadis.2022.166428 Article

S. Patra, S. Patil, S. Das, and S. K. Bhutia, "Epigenetic dysregulation in autophagy signaling as a driver of viral manifested oral carcinogenesis", BBA - Molecular Basis of Disease, vol.1868, pp.166517, Elsevier, August 2022, 10.1016/j.bbadis.2022.166517 Article

R. Prakash, E. Fauzia, Abu. J. Siddiqui, S. K. Yadav, N. Kumari, M. T. Shams, A. Naeem, P. P. Praharaj, M. A. Khan, S. K. Bhutia, M. Janowski, J. Boltze, and S. S. Raza, "Oxidative Stress-induced Autophagy Compromises Stem Cell Viability", Stem Cells, vol.40, no.5, pp.468-478, Oxford University Press, May 2022, 10.1093/stmcls/sxac018 Article

P. P. Naik, S. Panigrahi, R. Parida, P. P. Praharaj, C. S. Bhol, S. Patil, Nml. Manjunath, D. Ghosh, S. K. Patra, and S. K. Bhutia, "Metabostemness in cancer: Linking metaboloepigenetics and mitophagy in remodeling cancer stem cells", Stem Cell Reviews and Reports, vol.18, no.1, pp.198-213, Springer, January 2022, 10.1007/s12015-021-10216-9 Article

Show All Publications(+)

S. Patra, P. P. Praharaj, D. Klionsky, and S. K. Bhutia, "Vorinostat in autophagic cell death: A critical insight into autophagy-mediated, -associated and -dependent cell death for cancer prevention", Drug Discovery Today, vol.27, no.1, pp.269-279, Elsevier, January 2022, 10.1016/j.drudis.2021.08.004 Article

S. Patra, S. R. Mishra, B. P. Behera, K. K. Mahapatra, D. P. Panigrahi, C. S. Bhol, P. P. Praharaj, G. Sethi, S. K. Patra, and S. K. Bhutia, "Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives", Seminars in Cancer Biology, vol.80, pp.205-217, Elsevier 2022, 10.1016/j.semcancer.2020.05.008 Article

P. P. Praharaj, B. S. Patro, and S. K. Bhutia, "Dysregulation of mitophagy and mitochondrial homeostasis in cancer stem cells: Novel mechanism for anti-cancer stem cell-targeted cancer therapy", British Journal of Pharmacology, vol.179, no.22, pp.5015-5035, Wiley 2022, 10.1111/bph.15401 Article

S. Patra, S. Patil, S. Das, and S. K. Bhutia, "Epigenetic dysregulation in autophagy signaling as a driver of viral manifested oral carcinogenesis", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1868, no.11, pp.166517, Elsevier 2022, 10.1016/j.bbadis.2022.166517 Article

S. R. Mishra, K. K. Mahapatra, B. P. Behera, C. S. Bhol, P. P. Praharaj, D. P. Panigrahi, S. Patra, A. Singh, S. Patil, R. Dhiman, S. K. Patra, and S. K. Bhutia, "Inflammasomes in cancer: Effect of epigenetic and autophagic modulations", Seminars in Cancer Biology, vol.83, pp.399-412, Elsevier 2022, 10.1016/j.semcancer.2020.09.013 Article

S. Panda, B. P. Behera, S. K. Bhutia, C. K. Biswas, and S. Paul, "Rare transition metal doped hydroxyapatite coating prepared via microwave irradiation improved corrosion resistance, biocompatibility and anti-biofilm property of titanium alloy", Journal of Alloys and Compounds, vol.918, elsevier 2022, 10.1016/j.jallcom.2022.165662 Article

S. Mukhopadhyay, P. P. Praharaj, K. K. Mahapatra, S. Patil, and S. K. Bhutia, "Recent progress of autophagy signaling in tumor microenvironment and its targeting for possible cancer therapeutics", Seminars in cancer biology, vol.85, pp.196-208, Elsevier 2022, 10.1016/j.semcancer.2021.09.003 Article

S. K. Bhutia, "Vitamin D in autophagy signaling for health and diseases: Insights on potential mechanisms and future perspectives", Journal of Nutritional Biochemistry, vol.99, pp.108841, Elsevier 2022, 10.1016/j.jnutbio.2021.108841 Article

R. Prakash, E. Fauzia, Abu. J. Siddiqui, S. K. Yadav, N. Kumari, A. Singhai, M. A. Khan, M. Janowski, S. K. Bhutia, and S. S. Raza, "Oxidative Stress Enhances Autophagy-Mediated Death Of Stem Cells Through Erk1/2 Signaling Pathway - Implications For Neurotransplantations", Stem Cell Reviews and Reports, vol.17, no.6, pp.2347-2358., Springer, December 2021, 10.1007/s12015-021-10212-z Article

K. K. Mahapatra, S. R. Mishra, B. P. Behera, S. Patil, D. A. Gewirtz, and S. K. Bhutia, "The lysosome as an imperative regulator of autophagy and cell death", Cellular and Molecular Life Sciences, vol.78, pp.7435–7449, Springer, December 2021, 10.1007/s00018-021-03988-3 Article

S. Patra, B. Pradhan, R. Nayak, C. Behera, S. Das, S. K. Patra, T. Efferth, M. Jena, and S. K. Bhutia, "Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action", Phytomedicine, vol.90, pp.153554, Elsevier, September 2021, 10.1016/j.phymed.2021.153554 Article

S. Panda, C. S. Bhol, S. K. Bhutia, and S. Mohapatra, "DSPE-PEG-Coated Uniform Nitrogen-Doped Carbon Capsules for NIR-Mediated Synergistic Chemophototherapy of Skin Cancer", ACS applied Biomaterials, vol.4, pp.7059, American Chemical Society, September 2021, https://doi.org/10.1021/acsabm.1c00687 Article

S. R. Mishra, K. K. Mahapatra, B. P. Behera, S. Patra, C. S. Bhol, D. P. Panigrahi, P. P. Praharaj, A. Singh, S. Patil, R. Dhiman, and S. K. Bhutia, "Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics", The International Journal of Biochemistry & Cell Biology, vol.136, Elsevier, July 2021, 10.1016/j.biocel.2021.106013 Article

C. S. Bhol, S. Patil, B. B. Sahu, S. K. Patra, and S. K. Bhutia, "The clinical significance and correlative signaling pathways of paired box gene 9 in development and carcinogenesis", Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1876, no.1, Elsevier, May 2021, 10.1016/j.bbcan.2021.188561 Article

S. Panda, C. S. Bhol, S. K. Bhutia, and S. Mohapatra, "PEG–PEI-modified gated N-doped mesoporous carbon nanospheres for pH/NIR light-triggered drug release and cancer phototherapy", Journal of Materials Chemistry B, vol.9, pp.3666, RSC, March 2021, 10.1039/d1tb00362c Article

P. P. Praharaj, D. P. Panigrahi, C. S. Bhol, S. Patra, S. R. Mishra, K. K. Mahapatra, B. P. Behera, A. Singh, S. Patil, and S. K. Bhutia, "Mitochondrial rewiring through mitophagy and mitochondrial biogenesis in cancer stem cells: A potential target for anti-CSC cancer therapy", Cancer Letters, vol.498, pp.217-228, Elsevier, February 2021, https://doi.org/10.1016/j.canlet.2020.10.036 Article

P. P. Naik, S. Mukhopadhyay, P. P. Praharaj, C. S. Bhol, D. P. Panigrahi, K. K. Mahapatra, S. Patra, S. Saha, A. K. Panda, K. Panda, S. Paul, P. Aich, S. K. Patra, and S. K. Bhutia, "Secretory clusterin promotes oral cancer cell survival via inhibiting apoptosis by activation of autophagy in AMPK/mTOR/ULK1 dependent pathway", Life Sciences, vol.264, pp.118722, Elsevier, January 2021, https://doi.org/10.1016/j.lfs.2020.118722 Article

S. Patra, B. Pradhan, R. Nayak, C. Behera, K. C. Panda, S. Das, M. Jena, and S. K. Bhutia, "Apoptosis and autophagy modulating dietary phytochemicals in cancer therapeutics: Current evidences and future perspectives", Phytotherapy Research, vol.35, no.8, pp.4194-4214, Wiley 2021, 10.1002/ptr.7082 Article

S. Patra, B. Pradhan, R. Nayak, C. Behera, L. Rout, M. Jena, T. Efferth, and S. K. Bhutia, "Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics", Seminars in Cancer Biology, vol.73, pp.310-320, Elsevier 2021, 10.1016/j.semcancer.2020.10.010 Article

S. Patra, K. K. Mahapatra, P. P. Praharaj, D. P. Panigrahi, C. S. Bhol, S. R. Mishra, B. P. Behera, A. Singh, M. Jena, and S. K. Bhutia, "Intricate role of mitochondrial calcium signalling in mitochondrial quality control for regulation of cancer cell fate", Mitochondrion, vol.57, pp.230-240, Elsevier 2021, 10.1016/j.mito.2021.01.002 Article

A. Mishra, A. Behura, A. Kumar, L. Naik, A. Swain, M. Das, S. S. Sarangi, P. Dokania, V. Dirisala, S. K. Bhutia, A. Mishra, R. Singh, and R. Dhiman, "P2X7 receptor in multifaceted cellular signaling and its relevance as a potential therapeutic target in different diseases", European Journal of Pharmacology, vol.906, pp.174235, Elsevier 2021, 10.1016/j.ejphar.2021.174235 Article

A. Mishra, A. Behura, A. Kumar, A. Ghosh, L. Naik, S. Mawatwal, S. S. Mohanty, A. Mishra, S. Saha, S. K. Bhutia, R. Singh, and R. Dhiman, "Soybean lectin induces autophagy through P2RX7 dependent activation of NF-kB-ROS pathway to kill intracellular mycobacteria", Biochim Biophys Acta Gen Subj., vol.1865, no.2, pp.129806, Elsevier 2021, 10.1016/j.bbagen.2020.129806 Article

S. Mukhopadhyay and S. K. Bhutia, "Trends in CRISPR-Cas9 technology application in cancer", Progress in Molecular Biology and Translational Science, vol.178, pp.175-192, Elsevier 2021, 10.1016/bs.pmbts.2020.12.004 Article

B. Pradhan, S. Patra, C. Behera, R. Nayak, S. Patil, S. K. Bhutia, and M. Jena, "Enteromorpha compressa extract induces anticancer activity through apoptosis and autophagy in oral cancer", Molecular Biology Reports, vol.47, no.12, pp.9567-9578, Springer, December 2020, 10.1007/s11033-020-06010-4 Article

S. Mukhopadhyay, P. P. Praharaj, P. P. Naik, S. Talukdar, L. Emdad, P. B. Fisher, and S. K. Bhutia, "Identification of Annexin A2 as a key mTOR target to induce roller coaster pattern of autophagy fluctuation in stress", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1866, no.12, pp.165952, Elsevier, December 2020, 10.1016/j.bbadis.2020.165952 Article

B. Pradhan, S. Patra, R. Nayak, C. Behera, S. Nayak, B. B. Sahu, S. K. Bhutia, and M. Jena, "Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents", International Journal of Biological Macromolecules, vol.164, pp.4263-4278, Elsevier, December 2020, 10.1016/j.ijbiomac.2020.09.019 Article

S. Patra, C. S. Bhol, D. P. Panigrahi, P. P. Praharaj, B. Pradhan, M. Jena, and S. K. Bhutia, "Gamma irradiation promotes chemo-sensitization potential of gallic acid through attenuation of autophagic flux to trigger apoptosis in an NRF2 inactivation signalling pathway", Free Radical Biology and Medicine, vol.160, pp.111-124, Elsevier, November 2020, 10.1016/j.freeradbiomed.2020.06.022 Article

D. P. Panigrahi, C. S. Bhol, N. R, S. Nagini, S. Patil, T. K. Maiti, and S. K. Bhutia, "Abrus agglutinin inhibits oral carcinogenesis through inactivation of NRF2 signaling pathway", International Journal of Biological Macromolecules, vol.155, pp.1123-1132, Elsevier, July 2020, 10.1016/j.ijbiomac.2019.11.079 Article

S. Saha, K. K. Mahapatra, S. R. Mishra, S. Mallick, V. D. Negi, I. Sarangi, S. Patil, S. K. Patra, and S. K. Bhutia, "Bacopa monnieri inhibits apoptosis and senescence through mitophagy in human astrocytes", Food and Chemical Toxicology, vol.141, no.111367, Elsevier, July 2020, 10.1016/j.fct.2020.111367 Article

S. Saha, K. K. Mahapatra, S. R. Mishra, S. Mallick, V. D. Negi, I. Sarangi, S. Patil, S. K. Patra, and S. K. Bhutia, "Bacopa Monnieri Inhibits Apoptosis and Senescence Through Mitophagy in Human Astrocytes", Food and Chemical Toxicology, vol.141, pp.111367, Elsevier, July 2020, 10.1016/j.fct.2020.111367 Article

P. K. Panda, S. Patra, P. P. Naik, P. P. Praharaj, S. Mukhopadhyay, B. R. Meher, P. Gupta, R. S. Verma, T. K. Maiti, and S. K. Bhutia, "Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer", Journal of Cellular physiology, vol.235, no.3, pp.2776-2791, Wiley, March 2020, 10.1002/jcp.29182 Article

S. Patra, P. K. Panda, P. P. Naik, D. P. Panigrahi, P. P. Praharaj, C. S. Bhol, K. K. Mahapatra, P. Padhi, M. Jena, S. Patil, S. K. Patra, and S. K. Bhutia, "Terminalia bellirica extract induces anticancer activity through modulation of apoptosis and autophagy in oral squamous cell carcinoma", Food and Chemical Toxicology, vol.136, no.111073, Elsevier, February 2020, 10.1016/j.fct.2019.111073 Article

S. K. Bhutia and D. A. Gewirtz, "Autophagic molecules, mediators and modulators in cancer", Seminars in Cancer Biology, vol.66, pp.1-2, Elsevier 2020, 10.1016/j.semcancer.2020.04.004 Article

S. K. Bhutia, "Autophagy in tumor and tumor microenvironment", Biomedical and Life Sciences, ch.13, vol.1, no.1, pp.1-280, Springer 2020, 0.1007/978-981-15-6930-2 EditedBook

S. Patra, P. P. Praharaj, D. P. Panigrahi, B. Panda, C. S. Bhol, K. K. Mahapatra, S. R. Mishra, B. P. Behera, M. Jena, G. Sethi, S. Patil, S. K. Patra, and S. K. Bhutia, "Bioactive compounds from marine invertebrates as potent anticancer drugs: the possible pharmacophores modulating cell death pathways", Molecular Biology Report, vol.47, no.9, pp.7209-7228, Springer 2020, 10.1007/s11033-020-05709-8 Article

P. P. Praharaj, S. Patra, D. P. Panigrahi, S. K. Patra, and S. K. Bhutia, "Clusterin as modulator of carcinogenesis: A potential avenue for targeted cancer therapy", Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1875, no.2, Elsevier 2020, 10.1016/j.bbcan.2020.188500 Article

C. S. Bhol, D. P. Panigrahi, P. P. Praharaj, K. K. Mahapatra, S. Patra, S. R. Mishra, B. P. Behera, and S. K. Bhutia, "Epigenetic modifications of autophagy in cancer and cancer therapeutics", Seminars in Cancer Biology, vol.66, pp.22-33, Elsevier 2020, 10.1016/j.semcancer.2019.05.020 Article

B. Pradhan, S. Patra, R. Nayak, C. Behera, S. R. Dash, S. Nayak, B. B. Sahu, S. K. Bhutia, and M. Jena, "Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents", International Journal of Biological Macromolecules, vol.164, pp.4263-4278, Elsevier 2020, https://doi.org/10.1016/j.ijbiomac.2020.09.019 Article

D. P. Panigrahi, P. P. Praharaj, C. S. Bhol, K. K. Mahapatra, S. Patra, B. P. Behera, S. R. Mishra, and S. K. Bhutia, "The Emerging, Multifaceted Role of Mitophagy in Cancer and Cancer Therapeutics", Seminar in Cancer Biology, vol.66, pp.45-58, Elsevier 2020, 10.1016/j.semcancer.2019.07.015 Article

R. K. Das, S. Panda, C. S. Bhol, S. K. Bhutia, and S. Mohapatra, "N-Doped Carbon Quantum Dot (NCQD)-Deposited Carbon Capsules for Synergistic Fluorescence Imaging and Photothermal Therapy of Oral Cancer", Langmuir, vol.35, pp.15320, ACS, November 2019, https://doi.org/10.1021/acs.langmuir.9b03001 Article

K. K. Mahapatra, D. P. Panigrahi, P. P. Praharaj, C. S. Bhol, S. Patra, S. R. Mishra, B. P. Behera, and S. K. Bhutia, "Molecular interplay of autophagy and endocytosis in human health and diseases", Biological Reviews, vol.94, no.4, pp.1576-1590, Wiley, August 2019, 10.1111/brv.12515 Article

C. K. Das, A. Parekh, P. K. Parida, S. K. Bhutia, and M. Mandal, "Lactate dehydrogenase a regulates autophagy and tamoxifen resistance in breast cancer", Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1866, no.6, pp.1004-1018, Elsevier, June 2019, 10.1016/j.bbamcr.2019.03.004 Article

S. K. Bhutia, P. K. Panda, N. Sinha, P. P. Praharaj, C. S. Bhol, D. P. Panigrahi, K. K. Mahapatra, S. Saha, S. Patra, S. R. Mishra, B. P. Behera, S. Patil, and T. K. Maiti, "Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death", Pharmacological Research, vol.144, pp.8-18, Elsevier, June 2019, 10.1016/j.phrs.2019.04.001 Article

P. P. Praharaj, P. P. Naik, D. P. Panigrahi, C. S. Bhol, K. K. Mahapatra, S. Patra, G. Sethi, and S. K. Bhutia, "Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics", Cellular and Molecular Life Sciences, vol.76, no.9, pp.1641-1652., Springer, May 2019, 10.1007/s00018-018-2990-x Article

P. P. Naik, P. P. Praharaj, C. S. Bhol, D. P. Panigrahi, K. K. Mahapatra, S. Patra, S. Saha, and S. K. Bhutia, "Mitochondrial heterogeneity in stem cells", Stem Cells Heterogeneity - Novel Concepts, ch.11, vol.1123, pp.179-194, Springer, advances in experimental medicine and biology, April 2019, 10.1007/978-3-030-11096-3_11 Inbook

N. Sinha, B. R. Meher, P. P. Naik, P. K. Panda, S. Mukhopadhyay, T. K. Maiti, and S. K. Bhutia, "p73 induction by Abrus agglutinin facilitates Snail ubiquitination to inhibit epithelial to mesenchymal transition in oral cancer", Phytomedicine, vol.55, pp.179-190, Elsevier, March 2019, 10.1016/j.phymed.2018.08.003 Article

C. K. Das, B. C. Jena, I. Banerjee, S. Das, A. Parekh, S. K. Bhutia, and M. Mandal, "Exosome as a novel shuttle for delivery of therapeutics across biological barriers", Molecular Pharmaceutics, vol.16, no.1, pp.24-40, American Chemical Society, January 2019, 10.1021/acs.molpharmaceut.8b00901 Article

P. P. Naik, A. Birbrair, and S. K. Bhutia, "Mitophagy-driven metabolic switch reprograms stem cell fate", Cellular and Molecular Life Sciences, vol.76, no.1, pp.27-43, Springer, January 2019, 10.1007/s00018-018-2922-9 Article

S. Patra, D. P. Panigrahi, P. P. Praharaj, C. S. Bhol, K. K. Mahapatra, S. R. Mishra, B. P. Behera, M. Jena, and S. K. Bhutia, "Dysregulation of histone deacetylases in carcinogenesis and tumor progression: a possible link to apoptosis and autophagy", Cellular and Molecular Life Sciences, vol.76, no.17, pp.3263-3282, Springer 2019, 10.1007/s00018-019-03098-1 Article

J. Sophia, J. Kowshik, A. Dwivedi, S. K. Bhutia, B. Manavathi, R. Mishra, and S. Nagini, "Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3ß signalling pathway in oral cancer", Cell Death & Disease, vol.9, no.1087, Nature, October 2018, 10.1038/s41419-018-1126-4 Article

S. K. Bhutia, P. P. Naik, P. P. Praharaj, D. P. Panigrahi, C. S. Bhol, K. K. Mahapatra, S. Saha, and S. Patra, "Identification and characterization of stem cells in oral cancer", Stem Cell Niche, ch.11, vol.2002, pp.129-139, Humana, New York, methods in molecular biology book , September 2018, 10.1007/7651_2018_184 Inbook

S. Saha, D. P. Panigrahi, S. Patil, and S. K. Bhutia, "Autophagy in health and disease: A comprehensive review.", Biomedicine and Pharmacotherapy, vol.104, pp.485-495, Elsevier, August 2018, 10.1016/j.biopha.2018.05.007 Article

S. K. Bhutia, P. P. Praharaj, C. S. Bhol, D. P. Panigrahi, K. K. Mahapatra, S. Patra, S. Saha, D. N. Das, S. Mukhopadhyay, N. Sinha, P. K. Panda, and P. P. Naik, "Monitoring and measuring mammalian autophagy", Methods in Molecular Biology, pp.1-14, Springer, June 2018, 10.1007/7651_2018_159 Article

S. K. Bhutia, P. P. Praharaj, C. S. Bhol, D. P. Panigrahi, K. K. Mahapatra, S. Patra, S. Saha, D. N. Das, S. Mukhopadhyay, N. Sinha, P. K. Panda, and P. P. Naik, "Monitoring and measuring mammalian autophagy", Autophagy in Differentiation and Tissue Maintenance, ch.17, vol.1854, pp.209-222, Springer, part of the methods in molecular biology book , June 2018, 10.1007/7651_2018_159 Inbook

P. K. Panda, P. P. Naik, P. P. Praharaj, B. R. Meher, P. Gupta, R. S. Verma, T. K. Maiti, M. Shanmugam, A. Chinnathambi, S. Alharbi, G. Sethi, R. Agarwal, and S. K. Bhutia, "Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of ß-catenin in colon cancer stem cells.", Molecular Carcinogenesis, vol.57, no.5, pp.664-677, Wiley, May 2018, 10.1002/mc.22791 Article

P. P. Praharaj, S. K. Bhutia, S. Nagrath, R. Bitting, and G. Deep, "Circulating tumor cell-derived organoids: current challenges and promises in medical research and precision medicine", Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1869, no.2, pp.117-127, Elsevier, April 2018, 10.1016/j.bbcan.2017.12.005 Article

I., A. Paiva, P., P. Azevedo, L. Lousado, S. K. Bhutia, A. Salmina, A. Mintz, and A. Birbrair, "Glioblastoma-activated pericytes support tumor growth via immunosuppression", Cancer Medicine, vol.7, no.4, pp.1232-1239, Wiley, April 2018, 10.1002/cam4.1375 Article

P. K. Panda, P. P. Naik, B. R. Meher, D. N. Das, S. Mukhopadhyay, P. P. Praharaj, T. K. Maiti, and S. K. Bhutia, "PUMA dependent mitophagy by abrus agglutinin contributes to apoptosis through ceramide generation", Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1865, no.3, pp.480-495, Elsevier, March 2018, 10.1016/j.bbamcr.2017.12.002 Article

P. P. Naik, S. Mukhopadhyay, P. K. Panda, N. Sinha, C. K. Das, R. Mishra, S. Patil, and S. K. Bhutia, "Autophagy regulates cisplatin-induced stemness and chemoresistance via the upregulation of CD44, ABCB1 and ADAM17 in oral squamous cell carcinoma.", Cell Proliferation, vol.51, no.1, Wiley, February 2018, 10.1111/cpr.12411 Article

P. P. Naik, P. K. Panda, and S. K. Bhutia, "Oral cancer stem sells microenvironment", Stem Cell Microenvironments and Beyond, ch.11, vol.1041, pp.207-233, Springer Nature, advances in experimental medicine and biology book (aemb, volume 1041), December 2017, 10.1007/978-3-319-69194-7_11 Inbook

D. N. Das, P. K. Panda, N. Sinha, S. Mukhopadhyay, P. P. Naik, and S. K. Bhutia, "DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced p53-mediated apoptosis through activation of cytochrome P450/aryl hydrocarbon receptor.", Environmental Toxicology and Pharmacology, vol.55, pp.175-185, Elsevier, October 2017, 10.1016/j.etap.2017.08.012 Article

N. Sinha, P. K. Panda, P. P. Naik, T. K. Maiti, and S. K. Bhutia, "Abrus agglutinin targets cancer stem-like cells by eliminating self-renewal capacity accompanied with apoptosis in oral squamous cell carcinoma", Tumor Biology, vol.39, no.5, SAGE, May 2017, 10.1177/1010428317701634 Article

S. Mukhopadhyay, I. Schlaepfer, B. Bergman, P. K. Panda, P. P. Praharaj, P. P. Naik, R. Agarwal, and S. K. Bhutia, "ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway", Free Radical Biology and Medicine, vol.104, pp.199–213, Elsevier, March 2017, 10.1016/j.freeradbiomed.2017.01.007 Article

P. K. Panda, B. Behera, B. R. Meher, D. N. Das, S. Mukhopadhyay, N. Sinha, P. P. Naik, B. Roy, J. Das, S. Paul, T. Maiti, R. Agarwal, and S. K. Bhutia, "Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death", Molecular Carcinogenesis, vol.56, no.2, pp.389–401, Wiley, February 2017, 10.1002/mc.22502 Article

D. N. Das, P. K. Panda, P. P. Naik, S. Mukhopadhyay, N. Sinha, and S. K. Bhutia, "Phytotherapeutic approach: a new hope for polycyclic aromatic hydrocarbons induced cellular disorders, autophagic and apoptotic cell death.", Toxicology Mechanisms and Methods, vol.27, no.1, pp.1-17, Taylor & Francis, January 2017, 10.1080/15376516.2016.1268228 Article

N. Sinha, P. K. Panda, P. P. Naik, D. N. Das, S. Mukhopadhyay, T. K. Maiti, Mk. Shanmugam, A. Chinnathambi, Me. Zayed, Sa. Alharbi, G. Sethi, R. Agarwal, and S. K. Bhutia, "Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma.", Molecular Carcinogenesis, vol.56, no.11, pp.2400–2413, Wiley 2017, 10.1002/mc.22679 Article

S. Asthana, S. K. Bhutia, H. Sahoo, and S. Jha, "Chaotropes trigger conformational rearrangements differently in Concanavalin A", Journal of Chemical Sciences, vol.129, no.8, pp.1267-1276, Springer 2017, 10.1007/s12039-017-1333-z Article

D. N. Das, P. P. Naik, S. Mukhopadhyay, P. K. Panda, N. Sinha, B. R. Meher, and S. K. Bhutia, "Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis.", Free Radical Biology and Medicine, vol.112, pp.452-463, Elsiver 2017, 10.1016/j.freeradbiomed.2017.08.020 Article

P. P. Naik, D. N. Das, P. K. Panda, S. Mukhopadhyay, N. Sinha, P. P. Praharaj, R. Agarwal, and S. K. Bhutia, "Implications of cancer stem cells in developing therapeutic resistance in oral cancer", Oral Oncology, pp.122–135, Elsevier, November 2016, 10.1016/j.oraloncology.2016.10.008 Article

S. Mukhopadhyay, P. P. Naik, P. K. Panda, N. Sinha, D. N. Das, and S. K. Bhutia, "Serum starvation induces anti-apoptotic cIAP1 to promote mitophagy through ubiquitination", Biochemical and Biophysical Research Communications, vol.479, no.4, pp.940–946, Elsevier, October 2016, 10.1016/j.bbrc.2016.09.143 Article

D. N. Das, N. Sinha, P. P. Naik, P. K. Panda, S. Mukhopadhyay, S. K. Mallick, I. Sarangi, and S. K. Bhutia, "Mutagenic and genotoxic potential of native air borne particulate matter from industrial area of Rourkela city, Odisha, India", Environmental Toxicology and Pharmacology, vol.46, pp.131–139, Elsevier, September 2016, 10.1016/j.etap.2016.07.011 Article

S. K. Bhutia, B. Behera, D. Das, S. Mukhopadhyay, N. Sinha, P. Panda, P. Naik, S. K. Patra, M. Mandal, S. Sarkar, M. Menezes, S. Talukdar, T. Maiti, S. K. Das, D. Sarkar, and P. Fisher, "Abrus agglutinin is a potent anti-proliferative and anti-Angiogenic agent in human breast cancer", International Journal of Cancer, vol.139, no.2, pp.457-466, John wiley & sons, July 2016, 10.1002/ijc.30055 Article

D. N. Das, P. P. Naik, A. Nayak, P. K. Panda, S. Mukhopadhyay, N. Sinha, and S. K. Bhutia, "Bacopa monnieri-Induced Protective Autophagy Inhibits Benzo[a]pyrene-Mediated Apoptosis.", Phytotherapy Research, vol.30, no.11, pp.1794-1801, John Wiley & Sons, July 2016, 10.1002/ptr.5682 Article

S. Mukhopadhyay, N. Sinha, D. Das, P. Panda, P. Naik, and S. K. Bhutia, "Clinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects", Critical Reviews in Clinical Laboratory Sciences, vol.53, no.4, pp.228-252, Taylor & Francis, February 2016, 10.3109/10408363.2015.1135103 Article

S. Mukhopadhyay, D. Das, P. Panda, N. Sinha, P. Naik, A. Bissoyi, K. Pramanik, and S. K. Bhutia, "Autophagy protein Ulk1 promotes mitochondrial apoptosis through reactive oxygen species", Free Radical Biology and Medicine, vol.89, pp.311-321, Elsevier, December 2015, 10.1016/j.freeradbiomed.2015.07.159 Article

I. Pal, S. Parida, B., P. Banik, K. K. Dey, S. Chakraborty, S. K. Bhutia, and M. Mandal, "Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma", European Journal of Pharmacology, vol.765, pp.217-227, Elsevier, October 2015, 10.1016/j.ejphar.2015.08.039 Article

M. Deb, D. Sengupta, S. K. Rath, S. Kar, S. Parbin, A. Shilpi, N. Pradhan, S. K. Bhutia, S. Roy, and S. K. Patra, "Clusterin gene is predominantly regulated by histone modifications in human colon cancer and ectopic expression of the nuclear isoform induces cell death.", BBA Molecular Basis of Disease, vol.1852, no.8, pp.1630-1645, Elsevier, August 2015, DOI: 10.1016/j.bbadis.2015.04.021 Article

S. Dash, A. Panda, S. Pasayat, R. Dinda, A. Biswas, E., S. Mukhopadhyay, S. K. Bhutia, W. Kaminsky, and E. Sinn, "Oxidovanadium(v) complexes of aroylhydrazones incorporating heterocycles: synthesis, characterization and study of DNA binding, photo-induced DNA cleavage and cytotoxic activities", RSC Advances, vol.5, no.64, pp.51852-51867, Royal Society of Chemistry, June 2015, 10.1039/c4ra14369h Article

S. Dash, A. Panda, S. Pasayat, S. Majumder, A. Biswas, W. Kaminsky, S. Mukhopadhyay, S. K. Bhutia, and R. Dinda, "Evaluation of the cell cytotoxicity and DNA/BSA binding and cleavage activity of some dioxidovanadium(V) complexes containing aroylhydrazones", Journal of Inorganic Biochemistry, vol.144, pp.1-12, Elsevier, March 2015, 10.1016/j.jinorgbio.2014.12.018 Article

P. Panda, S. Mukhopadhyay, D. Das, N. Sinha, P. Naik, and S. K. Bhutia, "Mechanism of autophagic regulation in carcinogenesis and cancer therapeutics", Seminars in Cell and Developmental Biology, vol.39, pp.43-55, Elsevier, March 2015, 10.1016/j.semcdb.2015.02.013 Article

. Saswati, A. Chakraborty, S. Dash, A. Panda, R. Acharyya, A. Biswas, S. Mukhopadhyay, S. K. Bhutia, A. Crochet, Y. Patil, M. Nethajie, and R. Dinda, "Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu(I/II) complexes of thiosemicarbazone: special emphasis on their interactions with DNA", Dalton Transactions, vol.44, no.13, pp.6147-6157, Royal Society of Chemistry, February 2015, 10.1039/c4dt03764b Article

S. Mohapatra, S. Sahu, N. Sinha, and S. K. Bhutia, "Synthesis of a carbon-dot-based photoluminescent probe for selective and ultrasensitive detection of Hg2+ in water and living cells", Analyst, vol.140, no.4, pp.1221-1228, Royal Society of Chemistry, December 2015, 10.1039/c4an01386g Article

S. Dash, A. K. Panda, S. Pasayat, S. Majumder, A. Biswas, W. Kaminsky, S. Mukhopadhyay, S. K. Bhutia, and R. Dinda, "Evaluation of the cell cytotoxicity and DNA/BSA binding and cleavage activity of some dioxidovanadium(V) complexes containing aroylhydrazones", Journal of Inorganic Biochemistry, vol.144, pp.1-12, Elsevier Inc. 2015, 10.1016/j.jinorgbio.2014.12.018 Article

S. Pasayat, S. P. Dash, S. Majumder, R. Dinda, E. Sinn, H. Stoeckli, S. Mukhopadhyay, S. K. Bhutia, and P. Mitra, "Synthesis, structure, characterization and study of antiproliferative activity of dimeric and tetrameric oxidomolybdenum(VI) complexes of N,N'-disalicyloylhydrazine", Polyhedron, vol.80, pp.198-205, Elsevier, September 2014, 10.1016/j.poly.2014.04.007 Article

P. K. Panda, S. Mukhopadhyay, B. Behera, C. S. Bhol, S. Dey, D. N. Das, N. Sinha, A. Bissoyi, K. Pramanik, T. Maiti, and S. K. Bhutia, "Antitumor effect of soybean lectin mediated through reactive oxygen species-dependent pathway", Life Science, vol.111, no.1-2, pp.27-35, Elsevier, August 2014, 10.1016/j.lfs.2014.07.004 Article

S. Mukhopadhyay, P. K. Panda, N. Sinha, D. N. Das, and S. K. Bhutia, "Autophagy and apoptosis: where do they meet?", Apoptosis, vol.19, no.4, pp.555-566, Kluwer Academic Publishers, April 2014, 10.1007/s10495-014-0967-2 Article

B. Roy, A. K. Pattanaik, J. Das, S. K. Bhutia, B. Behera, P. Singh, and T. K. Maiti, "Role of PI3K/Akt/mTOR and MEK/ERK pathway in concanavalin a induced autophagy in HeLa cells", Chemico-Biological Interactions, vol.210, no.1, pp.96-102, Elsevier, March 2014, 10.1016/j.cbi.2014.01.003 Article

S. Mukhopadhyay, P. K. Panda, B. Behera, C. K. Das, Md. K. Hassan, D. N. Das, N. Sinha, A. Bissoyi, K. Pramanik, T. Maiti, and S. K. Bhutia, "In vitro and in vivo antitumor effects of peanut agglutinin through induction of apoptotic and autophagic cell death", Food and Chemical Toxicology, vol.64, pp.369-377, Elsevier, February 2014, 10.1016/j.fct.2013.11.046 Article

D. Das, P. Panda, S. Mukhopadhyay, N. Sinha, B. Mallick, B. Behera, T. Maiti, and S. K. Bhutia, "Prediction and validation of apoptosis through cytochrome P450 activation by benzo[a]pyrene", Chemico-Biological Interactions, vol.208, no.1, pp.8-17, Elsevier, February 2014, 10.1016/j.cbi.2013.11.005 Article

S. Mukhopadhyay, P. K. Panda, D. N. Das, N. Sinha, B. Behera, T. K. Maiti, and S. K. Bhutia, "Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspasemediated cell death", Acta Pharmacologica Sinica, vol.35, pp.814-824, APS, January 2014, 10.1038/aps.2014.15 Article

B. Azab, R. Dash, S. Das, S. K. Bhutia, S. Sarkar, Xue. N. Shen, B. Quinn, P. Dent, I. Dmitriev, X. Y. Wang, D. Curiel, M. Pellecchia, J. Reed, D. Sarkar, and P. Fisher, "Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV).", Journal of Cellular Physiology, vol.229, no.1, pp.34-43, Wiley, January 2014, 10.1002/jcp.24408 Article

S. Sahu, N. Sinha, S. K. Bhutia, M. Majhi, and S. Mohapatra, "Luminescent magnetic hollow mesoporous silica nanotheranostics for camptothecin delivery and multimodal imaging", Journal of Materials Chemistry B, vol.2, no.24, pp.3799-3808, Royal Society of Chemistry, December 2014, 10.1039/c3tb21669a Article

S. P. Dash, A. Panda, S. Pasayat,, R. Dinda, A. Biswas, E., Y. Patil, M. Nethaji, W. Kaminsky, S. Mukhopadhyay, and S. K. Bhutia, "Syntheses and structural investigation of some alkali metal ion-mediated LVVO2- (L2- =tridentate ONO ligands) species: DNA binding, photo-induced DNA cleavage and cytotoxic activities", Dalton Transactions, vol.43, no.26, pp.10139-10156, Royal Society of Chemistry, December 2014, 10.1039/c4dt00883a Article

S. Dash, A. Panda, S. Pasayat, R. Dinda, A. Biswas, E., Y. Patil, M. Nethaji, W. Kaminsky, S. Mukhopadhyay, and S. K. Bhutia, "Syntheses and structural investigation of some alkali metal ion-mediated LVVO2 - (L2-=tridentate ONO ligands) species: DNA binding, photo-induced DNA cleavage and cytotoxic activities", Dalton Transactions, vol.43, no.26, pp.10139-10156, Royal Society of Chemistry 2014, 10.1039/c4dt00883a Article

S. Pasayat, S. Dash, S. Majumder, R. Dinda, E. Sinn, H. Stoeckli, S. Mukhopadhyay, S. K. Bhutia, and P. Mitra, "Synthesis, structure, characterization and study of antiproliferative activity of dimeric and tetrameric oxidomolybdenum(VI) complexes of N,N'-disalicyloylhydrazine", Polyhedron, vol.80, pp.198-205, Elsevier Ltd 2014, 10.1016/j.poly.2014.04.007 Article

S. Dash, S. Pasayat, S. Bhakat, S. Roy, R. Dinda, E. T. Tiekink, S. Mukhopadhyay, S. K. Bhutia, M. Hardikar, B. Joshi, Y. P. Patil, and M. Nethaji, "Highly stable hexacoordinated nonoxidovanadium(IV) complexes of sterically constrained ligands: Syntheses, structure, and study of antiproliferative and insulin mimetic activity", Inorganic Chemistry, vol.52, no.24, pp.14096-14107, ACS, September 2013, 10.1021/ic401866x Article

N. Sinha, S. Mukhopadhyay, D. N. Das, P. K. Panda, and S. K. Bhutia, "Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer", Oral Oncology, vol.49, no.9, pp.854–862, Elsevier, September 2013, 10.1016/j.oraloncology.2013.06.010 Article

S. K. Bhutia, S. K. Das, B. Azab, M. E. Menezes, P. Dent, X. Y. Wang, D. Sarkar, and P. B. Fisher, "Targeting breast cancer-initiating/stem cells with melanoma differentiation-associated gene-7/interleukin-24", International Journal of Cancer, vol.133, no.11, pp.2726-2736, Wiley, July 2013, 10.1002/ijc.28289 Article

S. K. Das, S. K. Bhutia, B. Azab, T. P. Kegelman, L. Peachy, P. K. Santhekadur, S. Dasgupta, R. Dash, P. Dent, S. Grant, L. Emdad, M. Pellecchia, D. Sarkar, and P. B. Fisher, "MDA-9/Syntenin and IGFBP-2 promote angiogenesis in human melanoma", Cancer Research, vol.73, no.2, pp.844-854, AACR, January 2013, 10.1158/0008-5472.CAN-12-1681 Article

S. K. Bhutia, S. Mukhopadhyay, N. Sinha, D. N. Das, P. K. Panda, S. K. Patra, M. T. K, A. M, D. P, W. X, Da. S. K, S. D, and F. P. B, "Autophagy: Cancer's friend or foe?", Advances in Cancer Research, vol.118, pp.61-95, Academic Press, December 2013, 10.1016/B978-0-12-407173-5.00003-0 Article

S. Dash, S. Pasayat, S. Bhakat, S. Roy, R. Dinda, E., S. Mukhopadhyay, S. K. Bhutia, M. Hardikar, B. Joshi, Y. Patil, and M. Nethaji, "Highly stable hexacoordinated nonoxidovanadium(IV) complexes of sterically constrained ligands: Syntheses, structure, and study of antiproliferative and insulin mimetic activity", Inorganic Chemistry, vol.52, no.24, pp.14096-14107, American Chemical Society 2013, 10.1021/ic401866x Article

S. Das, S. K. Bhutia, U. Sokhi, B. Azab, Z. Z. Su, H. Boukerche, T. Anwar, E. Moen, D. Chatterjee, M. Pellecchia, D. Sarkar, and P. Fisher, "Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanoma", Cancer Res, vol.72, no.23, pp.6217–6226, NIH Public Access, December 2012, 10.1158/0008-5472.CAN-12-0402 Article

P. Venkatesan, S. K. Bhutia, A. Singh, S. Das, R. Dash, K. Chaudhury, D. Sarkar, P. Fisher, and M. Mandal, "AEE788 potentiates celecoxib-induced growth inhibition and apoptosis in human colon cancer cells", Life Sciences, vol.91, no.15-16, pp.789–799, Elsevier, October 2012, 10.1016/j.lfs.2012.08.024 Article

S. Kar, M. Deb, D. Sengupta, A. Shilpi, S. K. Bhutia, and S. K. Patra, "Intricacies of hedgehog signaling pathways: A perspective in tumorigenesis", Experimental Cell Research, vol.318, no.16, pp.1959–1972, Elsevier, May 2012, 10.1016/j.yexcr.2012.05.015 Article

B. Azab, R. Dash, S. K. Das, S. K. Bhutia, X. N. Shen, B. A. Quinn, S. Sarkar, X. Y. Wang, M. Hedvat, I. P. Dmitriev, D. T. Curiel, S. Grant, P. Dent, J. C. Reed, M. Pellecchia, D. Sarkar, and P. B. Fisher, "Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells", Journal of Cellular Physiology, vol.227, no.5, pp.2145-2153, Wiley, January 2012, 10.1002/jcp.22947 Article

S. K. Bhutia, S. Das, T. Kegelman, B. Azab, R. Dash, . Zhao, . Xiang, F. Rizzi, S. Bettuzzi, S. G. Lee, P. Dent, S. Grant, D. T. Curiel, D. Sarkar, and P. B. Fisher, "mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer", Journal of Cellular Physiology, vol.227, no.5, pp.1805-1813, Wiley, January 2012, 10.1002/jcp.22904 Article

S. Das, S. K. Bhutia, T. P. Kegelman, L. Peachy, R. A. Oyesanya, S. Dasgupta, U. K. Sokhi, B. Azab, R. Dash, B. A. Quinn, K. Kim, P. M. Barral, Z. Z. Su, H. Boukerche, D. Sarkar, and P. B. Fisher, "MDA-9/syntenin: a positive gatekeeper of melanoma metastasis", Frontiers in Bioscience, vol.17, sigma-aldrich, January 2012, 10.2741/3911 Article

D. Chen, B. K. Yoo, P. K. Santhekadur, R. Gredler, S. K. Bhutia, S. Das, C. Fuller, Zao. Z. Su, P. Fisher, and D. Sarkar, "Insulin-like growth factor binding protein-7 (IGFBP7) functions as a potential tumor suppressor in hepatocellular carcinoma", Clinical Cancer Research, vol.17, no.21, American Association for Cancer Research, November 2011, 10.1158/1078-0432.CCR-10-2774 Article

S. Mallick, S. Maiti, S. K. Bhutia, and T. Maiti, "Activation of RAW 264.7 cells by Astraeus hygrometricus-derived heteroglucan through MAP kinase pathway", Cell Biol International, vol.35, no.6, pp.617-621, Wiley, June 2011, 10.1042/CBI20100199 Article

S. K. Bhutia, S. K. Das, B. Azab, R. Dash, . Zhao, . Seok, P. Dent, D. T. Curiel, D. Sarkar, and P. B. Fisher, "Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24)", Autophagy, vol.7, no.9, pp.1076-1077, Taylor & Francis, April 2011, 10.4161/auto.7.9.16163 Article

S. K. Bhutia, T. P. Kegelman, S. K. Das, B. Azab, . Zhao, . Seok, D. Sarkar, and P. B. Fisher, "Astrocyte elevated gene-1 activates AMPK in response to cellular metabolic stress and promotes protective autophagy", Autophagy, vol.7, no.5, pp.547-548, Taylor & Francis Group, March 2011, 10.4161/auto.7.5.15078 Article

S. Maiti, S. K. Mallick, S. K. Bhutia, B. Behera, M. Mandal, and T. K. Maiti, "Antitumor effect of culinary-medicinal oyster mushroom, pleurotus ostreatus (Jacq.: Fr.) P. Kumm., derived protein fraction on tumor-bearing mice models", International Journal of Medicinal Mushrooms, vol.13, no.5, pp.427-40, Begell House, January 2011, 10.1615/IntJMedMushr.v13.i5.20 Article

S. K. Bhutia and T. K. Maiti, "Crabs eye (Abrus precatorius) seed and its immunomodulatory and antitumor properties", Nuts and Seeds in Health and Disease Prevention Nuts and Seeds in Health and Disease Prevention, ch.49, pp.409-415, Academic Press 2011, 10.1016/B978-0-12-375688-6.10049-0 Inbook

P. Dent, A. Yacoub, H. Hamed, M. Park, R. Dash, S. K. Bhutia, D. Sarkar, X. Y. Wang, P. Gupta, L. Emdad, I. Lebedeva, M. Sauane, Z. Z. Su, M. Rahmani, W. Broaddus, H. Young, M. Lesniak, S. Grant, D. Curiel, and P. Fisher, "The development of MDA-7/IL-24 as a cancer therapeutic", Pharmacology & Therapeutics, vol.128, no.2, pp.375–384, Elsevier, November 2010, 10.1016/j.pharmthera.2010.08.001 Article

S. Mallick, S. Maiti, S. K. Bhutia, and T. Maiti, "Antitumor properties of a heteroglucan isolated from astraeus hygrometricus on Dalton’s lymphoma bearing mouse", Food and Chemical Toxicology, vol.48, no.8-9, pp.2115–2121, Elsevier, September 2010, 10.1016/j.fct.2010.05.013 Article

S. K. Bhutia, S. K. Mallick, and T. K. Maity, "Tumour escape mechanisms and their therapeutic implications in combination tumour therapy", Cell Biological International, vol.34, no.5, pp.553-63, Wiley, May 2010, 10.1042/CBI20090206 Article

S. K. Bhutia, T. Kegelman, S. Das, B. Azab, Z. Z. Su, S. G. Lee, D. Sarkar, and P. Fisher, "Astrocyte elevated gene-1 induces protective autophagy", PNAS, vol.107, no.51, pp.22243–22248, National Academy of Sciences 2010, 10.1073/pnas.1009479107 Article

R. Dash, I. Dmitriev, . Z. Su, S. K. Bhutia, B. Azab, N. Vozhilla, A. Yacoub, P. Dent, D. T. Curiel, D. Sarkar, and P. B. Fisher, "Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells", Cancer Gene Therapy, vol.17, pp.447–456, Nature 2010, 10.1038/cgt.2009.91 Article

S. Das, S. K. Bhutia, U. Sokhi, R. Dash, B. Azab, D. Sarkar, and P. Fisher, "Human polynucleotide phosphorylase (hPNPaseold-35): an evolutionary conserved gene with an expanding repertoire of RNA degradation functions", Oncogene, vol.30, no.15, pp.1733-1734, PMC 2010, 10.1038/onc.2010.572 Article

S. Das, U. Sokhia, S. K. Bhutia, B. Azab, Z. Z. Su, D. Sarkar, and P. Fisher, "Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells", PNAS, vol.107, no.26, pp.11948–11953, National Academy of Sciences 2010, 10.1073/pnas.0914143107 Article

S. Mallick, S. Maiti, S. K. Bhutia, and T. Maiti, "Immunostimulatory properties of a polysaccharide isolated from astraeus hygrometricus", Journal of Medicinal Food, vol.13, no.3, pp.665-672, Mary Ann Liebert, Inc. 2010, 10.1089/jmf.2009.1300 Article

P. Dent, A. Yacoub, H. Hamed, M. Park, R. Dash, S. K. Bhutia, D. Sarkar, P. Gupta, L. Emdad, I. Lebedeva, M. Sauane, Z. Z. Su, M. Rahmani, W. Broaddus, H. Young, M. Lesniak, S. Grant, D. Curiel, and P. Fisher, "MDA-7/IL-24 as a cancer therapeutic: from bench to bedside", Anticancer Drugs, vol.21, no.8, pp.725-731, Wolters Kluwer Health 2010, 10.1097/CAD.0b013e32833cfbe1 Article

R. Dash, S. K. Bhutia, B. Azab, Z. Z. Su, B. Quinn, T. Kegelmen, S. Das, K. Kim, S. G. Lee, M. Park, A. Yacoub, M. Rahmani, L. Emdad, I. Dmitriev, X. Y. Wang1, D. Sarkar, S. Grant, P. Dent, D. Curiel, and P. Fisher, "mda-7/IL-24: A unique member of the IL-10 gene family promoting cancer-targeted toxicity", Cytokine & Growth Factor Reviews, vol.21, no.5, pp.381–391, Elsevier 2010, 10.1016/j.cytogfr.2010.08.004 Article

R. Dash, J. Richards, Z. Z. Su, S. K. Bhutia, B. Azab, M. Rahman, G. Dasmahapatra, A. Yacoub, P. Dent, I. Dmitriev, D. Curiel, S. Grant, M. Pellecchia, J. Reed, D. Sarkar, and P. Fisher, "Mechanism by which mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine", Cancer Research, vol.70, no.12, pp.5034-5045, AACR Publiication 2010, 10.1158/0008-5472.CAN-10-0563 Article

S. K. Bhutia, R. Dash, S. Das, B. Azab, Z. Z. Su, S. G. Lee, S. Grant, A. Yacoub, P. Dent, D. Curiel, D. Sarkar, and P. Fisher, "Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine mda-7/IL-24", Cancer Research, vol.70, no.9, pp.3667-3676, AACR Publication 2010, 10.1158/0008-5472.CAN-09-3647 Article

D. Ghosh, S. K. Bhutia, S. Mallick, I. Banerjee, and T. Maiti, "Stimulation of murine B and T lymphocytes by native and heat-denatured abrus agglutinin", Immunobiology, vol.214, no.3, pp.227–234, Elsevier, March 2009, 10.1016/j.imbio.2008.08.002 Article

S. K. Bhutia, S. Mallick, S. Maiti, D. Mishra, and T. Maiti, "Abrus abrin derived peptides induce apoptosis by targeting mitochondria in heLa cells", Cell Biology International, vol.33, no.7, pp.720–727, wiley 2009, 10.1016/j.cellbi.2009.04.012 Article

S. K. Bhutia, S. Mallick, and T. Maiti, "In vitro immunostimulatory properties of abrus lectins derived peptides in tumor bearing mice", Phytomedicine, vol.16, no.8, pp.776–782, Elsevier 2009, 10.1016/j.phymed.2009.01.006 Article

S. K. Bhutia, S. Mallick, S. Maiti, and T. Maiti, "Inhibitory effect of abrus abrin-derived peptide fraction against Dalton’s lymphoma ascites model", Phytomedicine, vol.16, no.4, pp.377–385, Elsevier 2009, 10.1016/j.phymed.2008.07.001 Article

S. K. Mallick, S. K. Bhutia, and T. K. Maiti, "Macrophage stimulation by polysaccharides isolated from barometer earthstar mushroom, astraeus hygrometricus (Pers.) morgan (gasteromycetideae)", International Journal of Medicinal Mushrooms, vol.11, no.3, pp.237-248, Begellhouse 2009, 10.1615/IntJMedMushr.v11.i3.30 Article

S. Maiti, S. K. Bhutia, S. Mallick, A. Kumar, N. Khadgi, and T. Maiti, "Antiproliferative and immunostimulatory protein fraction from edible mushrooms", Environmental Toxicology and Pharmacology, vol.26, no.2, pp.187–191, Elsevier 2008, 10.1016/j.etap.2008.03.009 Article

S. K. Bhutia, S. Mallick, S. Maiti, and T. Maiti, "Antitumor and proapoptotic effect of Abrus agglutinin derived peptide in Dalton's lymphoma tumor model", Chemico-Biological Interactions, vol.174, no.1, pp.11–18, Elsevier 2008, 10.1016/j.cbi.2008.04.043 Article

S. K. Bhutia, S. Mallick, S. Stevens, L. Prokai, J. Vishwanatha, and T. Maiti, "Induction of mitochondria-dependent apoptosis by abrus agglutinin derived peptides in human cervical cancer cell", Toxicology in Vitro, vol.22, no.2, pp.344–351, Elsevier 2008, 10.1016/j.tiv.2007.09.016 Article

S. K. Bhutia and T. Maiti, "Targeting tumors with peptides from natural sources", Trends in Biotechnology, vol.26, no.4, pp.210–217, Elsevier 2008, 10.1016/j.tibtech.2008.01.002 Article

S. Shah, D. Ghosh, S. K. Mallick, I. Sarangi, S. K. Bhutia, I. Banerje, S. Maiti, and T. K. Maiti, "Immunomodulatory and antitumor activities of water-soluble proteoglycan isolated from the fruiting bodies of culinary-medicinal oyster mushroom pleurotus ostreatus (Jacq.: Fr.) p. kumm. (agaricomycetideae)", International Journal of Medicinal Mushrooms, vol.9, no.2, pp.123-138, Begellhouse 2007, 10.1615/IntJMedMushr.v9.i2.30 Article

T. Das, S. Mallick, D. Paul, S. K. Bhutia, T. Bhattacharyya, and T. Maiti, "Microcontact printing of Concanavalin A and its effect on mammalian cell morphology", Journal of Colloid and Interface Science, vol.314, no.1, pp.71-79, Elsevier 2007, 10.1016/j.jcis.2007.05.017 Article

I. Sarangi, D. Ghosh, S. K. Bhutia, S. K. Mallick, and T. Maiti, "Anti-tumor and immunomodulating effects of Pleurotus ostreatus mycelia-derived proteoglycans", International Immunopharmacology, vol.6, no.8, pp.1287–1297, Elsevier 2006, 10.1016/j.intimp.2006.04.002 Article

Hide Publications (-)

Courses Taught

LS100 : Biology {Theory}
LS1001 : Biology {Theory}
LS206 : Cell and Molecular Biology {Theory}
LS311 : Cell and Cellular Techniques {Theory}
LS403 : Cell Biology {Theory}
LS405 : Cell Biology {Theory}
LS406 : Fundamentals of cell biology {Theory}
LS4407 : Cell Biology {Theory}
LS508 : Genomics and Proteomics {Theory}
LS511 : Genetics {Theory}
LS513 : Enzymology and Metabolism {Theory}
LS5304 : Genomics and Proteomics {Theory}
LS552 : Cell-cell Signaling {Theory}
LS581 : Cancer biology {Theory}
LS6004 : Cell Signalling {Theory}
LS604 : Cell Signalling {Theory}
LS276 : Cell and Molecular Biology laboratory {Practical}
LS4491 : Cell Biology Laboratory {Practical}
LS473 : Cell biology Laboratory {Practical}
LS475 : Immunology Laboratory {Practical}
LS574 : Computational Genomics and Proteomics Laboratory {Practical}

Research Scholars

Ph.D. Students [17]

Elucidating Mechanisms Of Benzo[a]pyrene Mediated Apoptotic And Autophagic Cell Death And Its Prevention With Phytotherapeutics

Durgesh Nandini Das

Enrolled: Jan 2011

Graduated : Dec 2015

Supervisor

Unraveling The Intricate Molecular Mechanism Between Apoptosis And Autophagy During Cellular Stress

Subhadip Mukhopadhyay

Enrolled: Jul 2011

Graduated : Nov 2016

Supervisor

Investigation Of The Epigenetic Regulators And Signaling Pathways Influencing Pluripotency Inducing Transcription Factors Mediated Tumorigenesis

Swayamsiddha Kar

Enrolled: Jul 2011

Graduated : Jan 2017

Co-Supervisor

Mechanism Of Tumor Inhibitory Potential Of Abrus Agglutinin In Oral Squamous Cell Carcinoma

Niharika Sinha

Enrolled: Jul 2011

Graduated : Apr 2017

Supervisor

Autophagy Dependent Cell Death, Senescence And Differentiation By Abrus Agglutinin In Cancer Therapeutics

Prashanta Kumar Panda

Enrolled: Sep 2011

Graduated : May 2017

Supervisor

Protective Autophagy In Inducing Stemness And Therapeutic Resistance In Oral Squamous Cell Carcinoma

Prajna Paramita Naik

Enrolled: Jul 2013

Graduated : Jan 2019

Supervisor

Deciphering The Epigenetic Mechanism Of Gene Regulation And Evaluation Of Medicinal Plant Products In Modulation Of Chromatin Modifications In Cancer

Nibedita Pradhan

Enrolled: Nov 2012

Graduated : Aug 2019

Co-Supervisor

Deciphering The Role Of Mtp18 In Mitophagy And Its Targeting For Apoptosis Induction In Oral Squamous Cell Carcinoma

Debasna Pritimanjari Panigrahi

Enrolled: Jul 2016

Graduated : May 2022

Supervisor

Unravelling The Molecular Connection Between Pax9 And Autophagy To Regulate Oral Carcinogenesis

Chandra Sekhar Bhol

Enrolled: Jul 2016

Graduated : Nov 2022

Supervisor

Defining The Role Of Clusterin In Autophagy-Related Signaling To Control Stemness And Survival Response In Oral Squamous Cell Carcinoma

Prakash Priyadarshi Praharaj

Enrolled: Jul 2015

Thesis Submitted : Mar 2023

Supervisor

Deciphering The Role Of Stonin 2 In Autophagy And Autophagic Lysosome Reformation To Control Cell Survival In Oral Squamous Cell Carcinoma

Kewal Kumar Mahapatra

Enrolled: Jul 2017

Continuing

Supervisor

Cancer Biology

Srimanta Patra

Enrolled: Jul 2018

Continuing

Supervisor

Cancer Biology

Soumya Ranjan Mishra

Enrolled: Jul 2018

Continuing

Supervisor

Cancer And Cell Death

Bishnu Prasad Behera

Enrolled: Jul 2019

Continuing

Supervisor

Cancer Cell Death And Autophagy

Amruta Singh

Enrolled: Aug 2020

Continuing

Supervisor

Autophagy And Cancer

Rakesh Kumar Kar

Enrolled: Jul 2022

Continuing

Supervisor

Cancer Biology And Autophagy

Priyadarshini Mishra

Enrolled: Jul 2022

Continuing

Supervisor

Dissertations

PG Dissertation

Puja Sahoo (413LS2049), "Ricinus agglutinin induced autophagy in Glioblastoma cells" - M.Sc. Supervisor 2014-15 Spring
Tanmayee Prusty (413LS2048), "APOPTOSIS AND AUTOPHAGY INDUCTION IN T98G CELLS WITH CONCANAVALIN A" - M.Sc. Supervisor 2014-15 Spring
Arnab Kapuria (414LS2029), "REGULATION OF AUTOPHAGY BY CALCIMYCIN IN THP-1 CELLS" - M.Sc. Co-supervisor 2015-16 Spring
Neethi Chandra Thathapudi (414LS2034), "ANTICANCER EFFICACY OF CHITOSAN COATED SILVER NANOPARTICLES MEDIATED THROUGH ROS PRODUCTION AND APOPTOTIC PATHWAY" - M.Sc. Co-supervisor 2015-16 Spring
Pankaj Kumar (414LS2055), "Biophysical Characterization of Antimicrobial Action of Nisin on Staphylococcus aureus" - M.Sc. Co-supervisor 2015-16 Spring
Balarama Krishna Gogineni (414LS2028), "Benzo (a) pyrene induced mitochondrial damage in HaCaT cells" - M.Sc. Supervisor 2016 Summer
Krishna C G (415LS2051), "EFFECT OF FIXATION AND INFECTION ON Caenorhabditis elegans" - M.Sc. Co-supervisor 2016-17 Spring
Sarbari Saha (415LS2064), "Investigating Autophagic status in Arabidopsis thaliana (Col-0) during osmotic stress" - M.Sc. Supervisor 2016-17 Spring
Suchitra Sahoo (415LS2066), "COMPARATIVE STUDY OF CRUDE EXTRACT FROM DIFFERENT VARIETIES OF Abrus precatorius SEEDS" - M.Sc. Supervisor 2016-17 Spring
Nilesh Kumar Meher (416LS2135), "Anti-cancer effect of cow urine on Oral cancer cell line" - M.Sc. Supervisor 2017-18 Spring
Trisha Kundu (416LS2064), "Bacopa monnieri protects from apoptosis and cellular senescence mediated by Benzo[a]pyrene" - M.Sc. Supervisor 2017-18 Spring
Jatin Sagoo (417LS2067), "Investigating anticancer potential of methanolic extract of CHLORELLA sp. against oral squamous cell carcinoma" - M.Sc. Supervisor 2018-19 Spring
Sunil Kumar Parida (417LS2061), "Elucidating the molecular interplay between apoptosis and autophagy induction by methanolic extract of Nannochloropsis sp. on Oral squamous carcinoma cell" - M.Sc. Supervisor 2018-19 Spring
Saptabarna Mukherjee (418LS2065), "The effect of salicylic acid in the induction and progression of autophagy in oral squamous cell carcinoma" - M.Sc. Supervisor 2019-20 Spring
Sunil Kumar Sahu (418LS2069), "Investigating the antitumor activity of procaine in oral cancer cell lines" - M.Sc. Supervisor 2019-20 Spring
Jutikana Mishra (419LS2070), "Clinicopathological features and associated risk factors of oral and neck related cancer patients of Assam, India" - M.Sc. Supervisor 2020-21 Spring
Sakshi Rani (419LS2140), "Investigation of growth inhibitory potential and mitophagy inducing activity of three different fractions of Bacopa monnieri extract in oral cancer cells" - M.Sc. Supervisor 2020-21 Spring
Indrajit Dutta (420LS2075), "Effects of arecoline on cell proliferation and mitochondrial dysfunction in oral squamous cell carcinoma" - M.Sc. Supervisor 2021-22 Spring
Nitish Kumar Mohanta (420LS2045), "Deciphering the molecular involvement of SIRT1 in oral carcinogenesis and identifying novel SIRT1 activators for oral cancer prevention" - M.Sc. Supervisor 2021-22 Spring
Sumit Sarkar (420LS2172), "Studying the effect of Butea monosperma extract on mitochondrial health" - M.Sc. Supervisor 2021-22 Spring

UG Dissertation

Subhasmita Purtty (414LS5090), "Delineating the Anticancer Propensity of Gamma-radiation Induced Conformational Shift in Gallic Acid against Oral Squamous Cell Carcinoma" - Integrated M.Sc. Supervisor 2019 Summer
Subhashree Swain (415LS5018), "Role of Bacopa monnieri in autophagy induction, inhibition of cell viability and migration in oral squamous cell carcinoma" - Integrated M.Sc. Supervisor 2019-20 Spring
Punyatoya Panda (416LS5020), "Identification and design of ULK1 inhibitors from phytochemical derivatives to inhibit protective autophagy in cancer" - Integrated M.Sc. Supervisor 2020-21 Spring

Awards and Honours

Odisha Bigyan Academy Young Scientist Award in Life Sciences 2015, 2017
ICMR International Fellowship for Young Indian Biomedical Scientist 2015-16, 2015
BD Biosciences winner for the research grant program 2013, 2013

Memberships / Fellowships

Odisha Bigyan Academy, 2012
Indian Association of Cancer Research, 2008
American Association of Cancer Research, 2008

Academic Identity

Orcid Id

Scopus Id

Researcher Id

Google Scholar Id

Sujit Kumar Bhutia

144

Publications

15

Sponsored Projects

0

Consultancy Projects

17

Doctoral Students

3

Continuing Education

20

PG Dissertation

Personal Information

Prof. Sujit Kumar Bhutia

Education Qualification

Experience

Teaching Experience

Post Doctoral Research Experience

Expertise Information

Research Group

Areas of Interest

Projects

Continuing Education

Publications

Google Scholar h-index

Google Scholar i10-index

0

Scopus h-index

Total Publications: 144

Courses Taught

Research Scholars

Ph.D. Students [17]

Dissertations

PG Dissertation

UG Dissertation

Awards and Honours

Awards and Honours

Memberships / Fellowships